University of Hertfordshire

A Pasteuria "eye view" of the nematode cuticle

Activity: Talk or presentationInvited talk

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Keith Davies - Speaker

Several species of endospore forming bacteria belonging to the Pasteuria group that are natural enemies of plant-parasitic nematodes have long been known to have potential to be developed into biological control agents. One of the current major constraints concerning their commercial development is their host specificity. Field populations of plant-parasitic nematodes usually occur as mixed populations and isolates of Pasteuria will adhere to one sub-population of phytonematodes but not another. Therefore, if isolates of Pasteuria are to be successfully deployed in the field an understanding of the mechanism by which endospores adhere to the nematode cuticle is essential to ensure that the endospore isolates applied can attach to the nematodes present in the soil. Resent research exploiting genomic sequence of Pasteuria has identified some 17 putative collagen-like proteins expressed on the surface of the endospore and these have been hypothesised to interact with a mucin-like protein present on the surface of the cuticle. Bioinformatic characterisation of these collagen-like proteins shows them to be diverse and possibly obtained through horizontal gene transfer from a variety of sources including viruses. Experiments using endospore adhesion bioassays to characterise the molecular nature of the second-stage juvenile cuticle surface have revealed that although mucin-like proteins may be involved the mechanism is more complex than hitherto thought and will be discussed in detail.
7 Jul 201911 Jul 2019

Event (Conference)

TitleSociety of Nematologists Annual Meeting 2019
Period7/07/1911/07/19
Web address (URL)
LocationNorth Carolina State University
CityRaleigh
CountryUnited States
Degree of recognitionInternational event

ID: 16952147