University of Hertfordshire

Dr Adam Young

Publications

  1. 2019
  2. Not all moderate disease is the same - Identification of disability trajectories among patients with rheumatoid arthritis and moderate disease activity

    Pan, Y., Norton, S., Gwinnutt, J. M., Kearsley-Fleet, L., Symmons, D. P. M., Lunt, M., Young, A., Hyrich, K. L. & Verstappen, S. M. M., 20 May 2019, In : PLoS ONE. 14, 5, e0215999.

    Research output: Contribution to journalArticle

  3. Is incident rheumatoid arthritis interstitial lung disease associated with methotrexate treatment? Results from a multivariate analysis in the ERAS and ERAN inception cohorts

    Kiely, P., Busby, A., Nikiphorou, E., Sullivan, K., Walsh, D., Creamer, P., Dixey, J. & Young, K., 29 Mar 2019, (Accepted/In press) In : BMJ Open.

    Research output: Contribution to journalArticle

  4. Discrete trajectories of resolving and persistent pain in people with rheumatoid arthritis despite undergoing treatment for inflammation: Results from three UK cohorts.

    McWilliams, D. F., Dawson, O., Young, K., Kiely, P., Ferguson, E. & Walsh, D., 15 Jan 2019, In : The Journal of Pain. 85, 9, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  5. 2018
  6. Sarilumab for Previously-Treated Moderate or Severe Rheumatoid Arthritis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal

    Bermejo, I., Ren, S., Simpson, E., Clowes, M., Scott, D. L., Young, K. & Stevenson, M., 1 Dec 2018, In : Pharmacoeconomics. 36, 12, p. 1427-1437 10 p.

    Research output: Contribution to journalArticle

  7. Validation of methods for converting the original Disease Activity Score (DAS) to the DAS28

    Carpenter, L., Norton, S., Nikiphorou, E., Kiely, P., Walsh, D., Dixey, J. & Young, K., 1 Dec 2018, In : Rheumatology International. 38, 12, p. 2297-2305 8 p.

    Research output: Contribution to journalArticle

  8. Tofacitinib for Treating Rheumatoid Arthritis After the Failure of Disease-Modifying Anti-rheumatic Drugs: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

    Uttley, L., Bermejo, I., Ren, S., Martyn-St James, M., Wong, R., Scott, D. L., Stevenson, M. & Young, K., 1 Sep 2018, In : Pharmacoeconomics. 36, 9, p. 1063-1072 10 p.

    Research output: Contribution to journalArticle

  9. Baricitinib for previously treated moderate or severe rheumatoid arthritis: An Evidence Review Group perspective of a NICE Single Technology Appraisal

    Ren, S., Bermejo, I., Simpson, E. L., Wong, R., Scott, D., Young, K. & Stevenson, M. D., 1 Jul 2018, In : Pharmacoeconomics. 36, 7, p. 769-778 10 p.

    Research output: Contribution to journalArticle

  10. The Association of Obesity with Adverse Disease Activity, Functional Ability and Quality of Life In Early Rheumatoid Arthritis: data from the Early Rheumatoid Arthritis Study/Early Rheumatoid Arthritis Network UK prospective cohorts

    Nikiphorou, E., Norton, S., Young, K., Dixey, J., Walsh, D., Helliwell, H. & Kiely, P., 1 Jul 2018, In : Rheumatology. 57, 7, p. 1194-1202 8 p.

    Research output: Contribution to journalArticle

  11. Interpretation of DAS28 and its components in the assessment of inflammatory and non-inflammatory aspects of rheumatoid arthritis

    Young, K., McWilliams, D. F., Kiely, P., Joharatnam, N., Wilson, D. & Walsh, D., 23 Mar 2018, In : BMC Rheumatology. 2, p. 1-12 12 p., 8.

    Research output: Contribution to journalArticle

  12. 2017
  13. The clinical effectiveness and cost-effectiveness of treat-to-target strategies in rheumatoid arthritis: a systematic review and cost-effectiveness analysis

    Wailoo, A., Hock, E. S., Stevenson, M., Martyn-St James, M., Rawdin, A., Simpson, E., Wong, R., Dracup, N., Scott, D. L. & Young, A., 1 Dec 2017, 71 ed. National Institute for Health Research (NIHR). 258 p. (Health Technology Assessment)

    Research output: Book/ReportOther report

  14. Reductions in Radiographic Progression in Early Rheumatoid Arthritis Over Twenty-Five Years: Changing Contribution From Rheumatoid Factor in Two Multicenter UK Inception Cohorts

    Carpenter, L., Norton, S., Nikiphorou, E., Jayakumar, K., McWilliams, D. F., Rennie, K. L., Dixey, J., Kiely, P., Walsh, D. A., Young, A. & on behalf of the Early Rheumatoid Arthritis Study and the Early Rheumatoid Arthritis Network, 28 Nov 2017, In : Arthritis Care and Research. 69, 12, p. 1809-1817 9 p.

    Research output: Contribution to journalArticle

  15. Certolizumab Pegol for Treating Rheumatoid Arthritis Following Inadequate Response to a TNF-α Inhibitor: An Evidence Review Group Perspective of a NICE Single Technology Appraisal

    Bermejo, I., Stevenson, M., Archer, R., Stevens, J. W., Goka, E., Clowes, M., Scott, D. L. & Young, A., 1 Nov 2017, In : Pharmacoeconomics. 35, 11, p. 1141-1151 11 p.

    Research output: Contribution to journalReview article

  16. Predicting responses in patients with rheumatoid arthritis to disease-modifying agents using baseline clinical data

    Gullick, N. J., Mian, A. N., Ibrahim, F., Walker, D., Hassell, A., Kiely, P. D. W., Walsh, D. A., Young, A., Scott, D. L., Lempp, H., Sturt, J., Georgopoulou, S., Prothero, L., Martin, N., Jenner, R., Neatrour, I., Baggott, R., Wailoo, A., Tosh, J., Galloway, J. & 6 othersKingsley, G., Scott, D., Tom, B., Zhong, Y., Mian, A. & on behalf of TITRATE Programme Investigators, 15 Sep 2017, In : Clinical and Experimental Rheumatology. 35, 5, p. 810-815 6 p.

    Research output: Contribution to journalArticle

  17. The Cost-effectiveness of Sequences of Biological Disease-modifying Antirheumatic Drug Treatment in England for Patients with Rheumatoid Arthritis Who Can Tolerate Methotrexate

    Stevenson, M. D., Wailoo, A. J., Tosh, J. C., Hernandez-Alava, M., Gibson, L. A., Stevens, J. W., Archer, R. J., Simpson, E. L., Hock, E. S., Young, A. & Scott, D. L., 1 Jul 2017, In : Journal of Rheumatology. 44, 7, p. 973-980 8 p.

    Research output: Contribution to journalArticle

  18. Achieving consensus on minimum data items (including core outcome domains) for a longitudinal observational cohort study in rheumatoid arthritis

    Nikiphorou, E., Mackie, S. L., Kirwan, J., Boers, M., Isaacs, J., Morgan, A. W. & Young, A., 1 Apr 2017, In : Rheumatology (United Kingdom). 56, 4, p. 550-555 6 p.

    Research output: Contribution to journalArticle

  19. Secular Changes in Clinical Features at Presentation of Rheumatoid Arthritis: Increase in Comorbidity But Improved Inflammatory States

    Nikiphorou, E., Norton, S., Carpenter, L., Dixey, J., Andrew Walsh, D., Kiely, P., Young, A. & on behalf of the Early Rheumatoid Arthritis Study and the Early Rheumatoid Arthritis Network Cohorts, 31 Jan 2017, In : Arthritis Care and Research. 69, 1, p. 21-27 7 p.

    Research output: Contribution to journalArticle

  20. 2016
  21. Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data

    McWilliams, D. F., Ferguson, E., Young, A., Kiely, P. D. W. & Walsh, D. A., 13 Dec 2016, In : Arthritis Research and Therapy. 18, 1, 12 p., 295.

    Research output: Contribution to journalReview article

  22. Association between rheumatoid arthritis disease activity, progression of functional limitation and long-term risk of orthopaedic surgery: Combined analysis of two prospective cohorts supports EULAR treat to target DAS thresholds

    Nikiphorou, E., Norton, S., Young, A., Carpenter, L., Dixey, J., Walsh, D. A., Kiely, P., Davies, P., Hill, L., Gough, A., Devlin, J., Emery, P., Waterhouse, L., James, D., Tate, H., Boys, C., Williams, P., White, D., Dart, H., Cox, N. & 31 othersStafford, S., Winfield, J., Seymour, A., Williams, R., Blunn, K., McDowell, J., Prouse, P., Andrews, S., Wilson, D., Magliano, M., Perks, U., Coulson, A., Hassle, A., Kirwan, M., Leone, F., Dunne, C., Hawley, L., Creamer, P., Taylor, J., Wilmott, W., Knights, S., Rowland-Axe, R., Green, S., Simmons, D., David, J., Cox, M., Bukhari, M., Evans, B., Batley, M., Oram, C. & ERAS and ERAN, 10 Nov 2016, In : Annals of the Rheumatic Diseases. 75, 12, p. 2080-2086 7 p.

    Research output: Contribution to journalArticle

  23. Erosive and osteoarthritic structural progression in early rheumatoid arthritis

    McWilliams, D. F., Marshall, M., Jayakumar, K., Doherty, S., Doherty, M., Zhang, W., Kiely, P. D. W., Young, A. & Walsh, D. A., 1 Aug 2016, In : Rheumatology (United Kingdom). 55, 8, p. 1477-1488 12 p.

    Research output: Contribution to journalArticle

  24. HLA-DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis

    Ling, S. F., Viatte, S., Lunt, M., Van Sijl, A. M., Silva-Fernandez, L., Symmons, D. P. M., Young, A., Macgregor, A. J. & Barton, A., 6 Jun 2016, In : Arthritis & rheumatology (Hoboken, N.J.). 68, 11, p. 2618-2628 11 p.

    Research output: Contribution to journalArticle

  25. Have Radiographic Progression Rates in Early Rheumatoid Arthritis Changed? A Systematic Review and Meta-analysis of Long-term Cohorts

    Carpenter, L., Nikiphorou, E., Sharpe, R., Norton, S., Rennie, K., Bunn, F., Scott, D., Dixey, J. & Young, A., 1 Jun 2016, In : Rheumatology. 55, 6, p. 1053-1065 13 p.

    Research output: Contribution to journalArticle

  26. Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: Systematic review and economic evaluation

    Stevenson, M., Archer, R., Tosh, J., Simpson, E., Everson-Hock, E., Stevens, J., Hernandez-Alava, M., Paisley, S., Dickinson, K., Scott, D., Young, A. & Wailoo, A., 4 May 2016, In : Health Technology Assessment. 20, 35, 672 p.

    Research output: Contribution to journalReview article

  27. 2015
  28. Rheumatoid Arthritis

    Nikiphorou, E. & Young, A., 25 Jun 2015, Landmark Papers in Rheumatology. Watts, R. A. & Scott, D. G. I. (eds.). OUP, p. 37-76

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  29. Direct health costs of inflammatory polyarthritis 10 years after disease onset: Results from the norfolk arthritis register

    Nikiphorou, E., Davies, C., Mugford, M., Cooper, N., Brooksby, A., Bunn, D. K., Young, A., Suzanne, S. M., Deborah, D. P. & MacGregor, A. J., 1 May 2015, In : Journal of Rheumatology. 42, 5, p. 794-798 5 p.

    Research output: Contribution to journalArticle

  30. The effect of disease severity and comorbidity on length of stay for orthopedic surgery in rheumatoid arthritis: Results from 2 UK inception cohorts, 1986-2012

    Nikiphorou, E., Morris, S., Dixey, J., Williams, P. L., Kiely, P., Walsh, D. A., MacGregor, A. & Young, A., 1 May 2015, In : Journal of Rheumatology. 42, 5, p. 778-785 8 p.

    Research output: Contribution to journalArticle

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