University of Hertfordshire

Dr Mahmoud Iravani Reader in Neuropharmacology

Reader

Publications

  1. 2019
  2. Contractile dysfunction and nitrergic dysregulation in small intestine of a primate model of Parkinson’s disease: contractile dysfunction in MPTP-treated primate ileum

    Coletto, E., Dolan, J. S., Pritchard, S., Gant, A., Hikima, A., Jackson, M. J., Benham, C., Chaudhuri, K. R., Rose, S., Jenner, P. & Iravani, M., 10 Jun 2019, In : npj Parkinson's Disease. 5, 10, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  3. 2018
  4. Kv7 channel regulation of colonic motility in mice

    Keating, C., Hassan, A-A. & Iravani, M., 2018, In : Neurogastroenterology and Motility. 30, S1

    Research output: Contribution to journalMeeting abstract

  5. 2017
  6. Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease

    Modo, M., Crum, W. R., Gerwig, M., Vernon, A. C., Patel, P., Jackson, M. J., Rose, S., Jenner, P. & Iravani, M. M., 24 Jul 2017, In : PLoS ONE. 12, 7, p. e0180733 21 p.

    Research output: Contribution to journalArticle

  7. Altered detrusor contractility in MPTP-treated common marmosets with bladder hyperreflexia

    Pritchard, S., Hikima, A., Jackson, M., Lione, L., Benham, C., Chaudhuri, K. R., Rose, S., Jenner, P. & Iravani, M., 17 May 2017, In : PLoS ONE. 12, 5, 19 p., e0175797.

    Research output: Contribution to journalArticle

  8. 2016
  9. Arylalkylpiperazines for use as neuroprotective agents: Arlyalkylpiperazines and neuroprotection

    Iravani, M., 7 Apr 2016, Patent No. WO2016051155 A1, Priority date 29 Sep 2014

    Research output: Patent

  10. 2014
  11. Loss of locus coeruleus noradrenergic neurons alters the inflammatory response to LPS in substantia nigra but does not affect nigral cell loss

    Iravani, M. M., Sadeghian, M., Rose, S. & Jenner, P., 1 Dec 2014, In : Journal of Neural Transmission. 121, 12, p. 1493-1505

    Research output: Contribution to journalArticle

  12. The H3 receptor agonist immepip does not affect l-dopa-induced abnormal involuntary movements in 6-OHDA-lesioned rats

    Papathanou, M., Jenner, P., Iravani, M. M., Jackson, M., Stockwell, K., Strang, I., Zeng, B-Y., McCreary, A. & Rose, S., 15 Oct 2014, In : European Journal of Pharmacology. 741, p. 304-310

    Research output: Contribution to journalArticle

  13. Physiological and Functional Changes in the Colon of MPTP-Treated Common Marmosets

    Coletto, E., Tough, I., Hikima, A., Iravani, M. M., Chaudhuri, K. R., Jenner, P., Cox, H. & Rose, S., May 2014, In : Movement disorders. 29, Suppl 1, 1525.

    Research output: Contribution to journalMeeting abstract

  14. 2013
  15. The spontaneous and neurogenic contractile responses of the isolated bladder smooth muscle are markedly enhanced in MPTP treated common marmoset (Callithrix jacchus)

    Pritchard, S., Jackson, M., Lione, L., Benham, C., Rose, S., Jenner, P. & Iravani, M. M., Dec 2013, In : pA2 online. 11, 3, 208P.

    Research output: Contribution to journalMeeting abstract

  16. Increase in the number of striatal neuronal nitric oxide synthase immunoreactive (nNOS-ir) interneurones in MPTP-treated common marmosets primed for and displaying levodopa-induced dyskinesia

    Peeris, M., Geraldes, L., Jackson, M., Hikima, A., Broadstock, M., Rose, S., Jenner, P. & Iravani, M. M., 2013, In : pA2 online. 11, 3, 2 p., 219P.

    Research output: Contribution to journalMeeting abstract

  17. 2012
  18. Lipopolysaccharide-induced nigral inflammation leads to increased IL-1β tissue content and expression of astrocytic glial cell line-derived neurotrophic factor.

    Iravani, M. M., Sadeghian, M., Leung, C. C. M., Jenner, P. & Rose, S., 29 Feb 2012, In : Neuroscience Letters. 510, 2, p. 138-142 5 p.

    Research output: Contribution to journalArticle

  19. Striatal plasticity in Parkinson's disease and L-DOPA induced dyskinesia

    Iravani, M. M., McCreary, A. C. & Jenner, P., 18 Jan 2012, In : Parkinsonism and Related Disorders. 18, S1, p. 123-125 3 p.

    Research output: Contribution to journalArticle

  20. 2011
  21. Mechanisms underlying the onset and expression of levodopa-induced dyskinesia and their pharmacological manipulation

    Iravani, M. M. & Jenner, P., Dec 2011, In : Journal of Neural Transmission. 118, 12, p. 1661-1690 30 p.

    Research output: Contribution to journalLiterature review

  22. The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression

    Brzozowski, M. J., Alcantara, S. L., Iravani, M. M., Rose, S. & Jenner, P., 2 Aug 2011, In : Brain Research. 1404, p. 21-30 10 p.

    Research output: Contribution to journalArticle

  23. 2010
  24. Morphological changes in serotoninergic neurites in the striatum and globus pallidus in levodopa primed MPTP treated common marmosets with dyskinesia

    Zeng, B-Y., Iravani, M. M., Jackson, M. J., Rose, S., Parent, A. & Jenner, P., Dec 2010, In : Neurobiology of Disease. 40, 3, p. 599-607 9 p.

    Research output: Contribution to journalArticle

  25. Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or L-DOPA in MPTP-treated common marmosets

    Stockwell, K. A., Scheller, D. K. A., Smith, L. A., Rose, S., Iravani, M. M., Jackson, M. J. & Jenner, P., Jan 2010, In : Experimental Neurology. 221, 1, p. 79-85 7 p.

    Research output: Contribution to journalArticle

  26. 2009
  27. Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction

    Stockwell, K. A., Scheller, D., Rose, S., Jackson, M. J., Tayarani-Binazir, K., Iravani, M. M., Smith, L. A., Olanow, C. W. & Jenner, P., Oct 2009, In : Experimental Neurology. 219, 2, p. 533-542 10 p.

    Research output: Contribution to journalArticle

  28. An immunohistochemical and stereological analysis of PSI-induced nigral neuronal degeneration in the rat

    Bukhatwa, S., Iravani, M. M., Zeng, B-Y., Cooper, J. D., Rose, S. & Jenner, P., Apr 2009, In : Journal of Neurochemistry. 109, 1, p. 52-59 8 p.

    Research output: Contribution to journalArticle

  29. 2008
  30. Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response

    Iravani, M. M., Sadeghian, M., Leung, C. C. M., Tel, B. C., Rose, S., Schapira, A. H. & Jenner, P., Aug 2008, In : Experimental Neurology. 212, 2, p. 522-531 10 p.

    Research output: Contribution to journalArticle

  31. Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems

    MacInnes, N., Iravani, M. M., Perry, E., Piggott, M., Perry, R., Jenner, P. & Ballard, C., Jun 2008, In : Journal of Neural Transmission. 115, 6, p. 869-878 10 p.

    Research output: Contribution to journalArticle

  32. Continuous delivery of ropinirole reverses motor deficits without dyskinesia induction in MPTP-treated common marmosets

    Stockwell, K. A., Virley, D. J., Perren, M., Iravani, M. M., Jackson, M. J., Rose, S. & Jenner, P., May 2008, In : Experimental Neurology. 211, 1, p. 172-179 8 p.

    Research output: Contribution to journalArticle

  33. Continuous vs pulsatile administration of rotigotine in rat and monkey models of Parkinson's disease: A comparison

    Scheller, D. K. A., Schmidt, W. J., Jackson, M. J., Ruess, U., Stockwell, K., Heindl, M., Iravani, M. M., Tayarani-Binazir, K., Rose, S. & Jenner, P., 2008, In : Movement disorders. 23, Supp 1, p. S86 1 p., 249.

    Research output: Contribution to journalMeeting abstract

  34. 2006
  35. Inhibition or Treatment of Dyskinesia

    Iravani, M. M. & Jenner, P., 24 Aug 2006, IPC No. A61K 31/00 (2006.01), A61K 31/195 (2006.01), A61K 45/06 (2006.01), A61P 25/14 (2006.01), Patent No. WO/2006/087577

    Research output: Patent

  36. MPTP treatment of common marmosets impairs proteasomal enzyme activity and decreases expression of structural and regulatory elements of the 26S proteasome

    Zeng, B-Y., Iravani, M. M., Lin, S. T., Irifune, M., Kuoppamaki, M., Al-Barghouthy, G., Smith, L., Jackson, M. J., Rose, S., Medhurst, A. D. & Jenner, P., Apr 2006, In : European Journal of Neuroscience. 23, 7, p. 1766-1774 9 p.

    Research output: Contribution to journalArticle

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