University of Hertfordshire

Characterisation of copper oxide nanoparticles for antimicrobial applications

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Characterisation of copper oxide nanoparticles for antimicrobial applications. / Ren, Guogang; Hu, D.; Cheng, E.W.C.; Vargas-Reus, M.A.; Reip, P.; Allaker, R.

In: International Journal of Antimicrobial Agents, Vol. 33, No. 6, 2009, p. 587-590.

Research output: Contribution to journalArticle

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Ren, Guogang ; Hu, D. ; Cheng, E.W.C. ; Vargas-Reus, M.A. ; Reip, P. ; Allaker, R. / Characterisation of copper oxide nanoparticles for antimicrobial applications. In: International Journal of Antimicrobial Agents. 2009 ; Vol. 33, No. 6. pp. 587-590.

Bibtex

@article{b2e2b5a80e164f3d9946ac522b347a10,
title = "Characterisation of copper oxide nanoparticles for antimicrobial applications",
abstract = "Copper oxide (CuO) nanoparticles were characterised and investigated with respect to potential antimicrobial applications. It was found that nanoscaled CuO, generated by thermal plasma technology, contains traces of pure Cu and Cu2O nanoparticles. Transmission electron microscopy (TEM) demonstrated particle sizes in the range 20–95 nm. TEM energy dispersive spectroscopy gave the ratio of copper to oxygen elements as 54.18{\%} to 45.26{\%}. The mean surface area was determined as 15.69 m2/g by Brunau–Emmet–Teller (BET) analysis. CuO nanoparticles in suspension showed activity against a range of bacterial pathogens, including meticillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli, with minimum bactericidal concentrations (MBCs) ranging from 100 μg/mL to 5000 μg/mL. The ability of CuO nanoparticles to reduce bacterial populations to zero was enhanced in the presence of sub-MBC concentrations of silver nanoparticles. Studies of CuO nanoparticles incorporated into polymers suggest release of ions may be required for optimum killing.",
keywords = "nanoparticle, copper oxide, CuO, antimicrobial, cross-infection control",
author = "Guogang Ren and D. Hu and E.W.C. Cheng and M.A. Vargas-Reus and P. Reip and R. Allaker",
note = "Original article can be found at : http://www.sciencedirect.com/ Copyright Elsevier [Full text of this article is not available in the UHRA]",
year = "2009",
doi = "10.1016/j.ijantimicag.2008.12.004",
language = "English",
volume = "33",
pages = "587--590",
journal = "International Journal of Antimicrobial Agents",
issn = "0924-8579",
publisher = "Elsevier",
number = "6",

}

RIS

TY - JOUR

T1 - Characterisation of copper oxide nanoparticles for antimicrobial applications

AU - Ren, Guogang

AU - Hu, D.

AU - Cheng, E.W.C.

AU - Vargas-Reus, M.A.

AU - Reip, P.

AU - Allaker, R.

N1 - Original article can be found at : http://www.sciencedirect.com/ Copyright Elsevier [Full text of this article is not available in the UHRA]

PY - 2009

Y1 - 2009

N2 - Copper oxide (CuO) nanoparticles were characterised and investigated with respect to potential antimicrobial applications. It was found that nanoscaled CuO, generated by thermal plasma technology, contains traces of pure Cu and Cu2O nanoparticles. Transmission electron microscopy (TEM) demonstrated particle sizes in the range 20–95 nm. TEM energy dispersive spectroscopy gave the ratio of copper to oxygen elements as 54.18% to 45.26%. The mean surface area was determined as 15.69 m2/g by Brunau–Emmet–Teller (BET) analysis. CuO nanoparticles in suspension showed activity against a range of bacterial pathogens, including meticillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli, with minimum bactericidal concentrations (MBCs) ranging from 100 μg/mL to 5000 μg/mL. The ability of CuO nanoparticles to reduce bacterial populations to zero was enhanced in the presence of sub-MBC concentrations of silver nanoparticles. Studies of CuO nanoparticles incorporated into polymers suggest release of ions may be required for optimum killing.

AB - Copper oxide (CuO) nanoparticles were characterised and investigated with respect to potential antimicrobial applications. It was found that nanoscaled CuO, generated by thermal plasma technology, contains traces of pure Cu and Cu2O nanoparticles. Transmission electron microscopy (TEM) demonstrated particle sizes in the range 20–95 nm. TEM energy dispersive spectroscopy gave the ratio of copper to oxygen elements as 54.18% to 45.26%. The mean surface area was determined as 15.69 m2/g by Brunau–Emmet–Teller (BET) analysis. CuO nanoparticles in suspension showed activity against a range of bacterial pathogens, including meticillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli, with minimum bactericidal concentrations (MBCs) ranging from 100 μg/mL to 5000 μg/mL. The ability of CuO nanoparticles to reduce bacterial populations to zero was enhanced in the presence of sub-MBC concentrations of silver nanoparticles. Studies of CuO nanoparticles incorporated into polymers suggest release of ions may be required for optimum killing.

KW - nanoparticle

KW - copper oxide

KW - CuO

KW - antimicrobial

KW - cross-infection control

U2 - 10.1016/j.ijantimicag.2008.12.004

DO - 10.1016/j.ijantimicag.2008.12.004

M3 - Article

VL - 33

SP - 587

EP - 590

JO - International Journal of Antimicrobial Agents

T2 - International Journal of Antimicrobial Agents

JF - International Journal of Antimicrobial Agents

SN - 0924-8579

IS - 6

ER -