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Co-Culture of Keratinocyte-Staphylococcus aureus on Cu-Ag-Zn/CuO and Cu-Ag-W Nanoparticle Loaded Bacterial Cellulose:PMMA Bandages. / Ren, Guogang; Edirisinghe, Mohan; Altun, Esra; Aydogdu, Mehmet Onur; Crabbe-Mann, Maram; Ahmed, Jubair.

In: Macromolecular Materials and Engineering, Vol. 304, No. 1, 1800537, 01.01.2019.

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Ren, Guogang ; Edirisinghe, Mohan ; Altun, Esra ; Aydogdu, Mehmet Onur ; Crabbe-Mann, Maram ; Ahmed, Jubair. / Co-Culture of Keratinocyte-Staphylococcus aureus on Cu-Ag-Zn/CuO and Cu-Ag-W Nanoparticle Loaded Bacterial Cellulose:PMMA Bandages. In: Macromolecular Materials and Engineering. 2019 ; Vol. 304, No. 1.

Bibtex

@article{1ec20ea7ee444253afffb99459969af4,
title = "Co-Culture of Keratinocyte-Staphylococcus aureus on Cu-Ag-Zn/CuO and Cu-Ag-W Nanoparticle Loaded Bacterial Cellulose:PMMA Bandages",
abstract = "Pressurized gyration and its sister processes are novel methods to produce polymeric fibers. Potential applications for such fibers include wound dressings, tissue engineering scaffolds, and filters. This study reports on a pressurized gyration technique that employs pressured N2 gas to prepare biocompatible wound dressing bandages from bacterial cellulose and poly (methylmethacrylate) polymer blended with alloyed antimicrobial nanoparti-cles. Resulting bandages are manufactured with high product yield and char-acterized for their chemical, physical, and mechanical properties. Increased density in solutions with additional antimicrobial nanoparticles results in increased fiber diameters. Also, addition of antimicrobial nanoparticles enhances ultimate tensile strength and Young’s modulus of the bandages. Typical molecular bonding in the bandages is confirmed by Fourier-transform infrared spectroscopy, with peaks that have higher intensity and narrowing points being caused by additional antimicrobial nanoparticles. More so, the cellular response to the bandages and the accompanying antimicrobial activity are studied in detail by in vitro co-culture of Staphylococcus aureusand keratinocytes. Antimicrobial nanoparticle-loaded bandage samples show increased cell viability and bacteria inhibition during co-culture and are found to have a promising future as epidermal wound dressing materials.",
keywords = "antimicrobial metallics, bacterial cellulose, bandage properties, cellular and bacteria co-cultures, polymers",
author = "Guogang Ren and Mohan Edirisinghe and Esra Altun and Aydogdu, {Mehmet Onur} and Maram Crabbe-Mann and Jubair Ahmed",
note = "{\circledC} 2018 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.",
year = "2019",
month = "1",
day = "1",
doi = "10.1002/mame.201800537",
language = "English",
volume = "304",
journal = "Macromolecular Materials and Engineering",
issn = "1439-2054",
publisher = "Wiley",
number = "1",

}

RIS

TY - JOUR

T1 - Co-Culture of Keratinocyte-Staphylococcus aureus on Cu-Ag-Zn/CuO and Cu-Ag-W Nanoparticle Loaded Bacterial Cellulose:PMMA Bandages

AU - Ren, Guogang

AU - Edirisinghe, Mohan

AU - Altun, Esra

AU - Aydogdu, Mehmet Onur

AU - Crabbe-Mann, Maram

AU - Ahmed, Jubair

N1 - © 2018 The Authors. Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Pressurized gyration and its sister processes are novel methods to produce polymeric fibers. Potential applications for such fibers include wound dressings, tissue engineering scaffolds, and filters. This study reports on a pressurized gyration technique that employs pressured N2 gas to prepare biocompatible wound dressing bandages from bacterial cellulose and poly (methylmethacrylate) polymer blended with alloyed antimicrobial nanoparti-cles. Resulting bandages are manufactured with high product yield and char-acterized for their chemical, physical, and mechanical properties. Increased density in solutions with additional antimicrobial nanoparticles results in increased fiber diameters. Also, addition of antimicrobial nanoparticles enhances ultimate tensile strength and Young’s modulus of the bandages. Typical molecular bonding in the bandages is confirmed by Fourier-transform infrared spectroscopy, with peaks that have higher intensity and narrowing points being caused by additional antimicrobial nanoparticles. More so, the cellular response to the bandages and the accompanying antimicrobial activity are studied in detail by in vitro co-culture of Staphylococcus aureusand keratinocytes. Antimicrobial nanoparticle-loaded bandage samples show increased cell viability and bacteria inhibition during co-culture and are found to have a promising future as epidermal wound dressing materials.

AB - Pressurized gyration and its sister processes are novel methods to produce polymeric fibers. Potential applications for such fibers include wound dressings, tissue engineering scaffolds, and filters. This study reports on a pressurized gyration technique that employs pressured N2 gas to prepare biocompatible wound dressing bandages from bacterial cellulose and poly (methylmethacrylate) polymer blended with alloyed antimicrobial nanoparti-cles. Resulting bandages are manufactured with high product yield and char-acterized for their chemical, physical, and mechanical properties. Increased density in solutions with additional antimicrobial nanoparticles results in increased fiber diameters. Also, addition of antimicrobial nanoparticles enhances ultimate tensile strength and Young’s modulus of the bandages. Typical molecular bonding in the bandages is confirmed by Fourier-transform infrared spectroscopy, with peaks that have higher intensity and narrowing points being caused by additional antimicrobial nanoparticles. More so, the cellular response to the bandages and the accompanying antimicrobial activity are studied in detail by in vitro co-culture of Staphylococcus aureusand keratinocytes. Antimicrobial nanoparticle-loaded bandage samples show increased cell viability and bacteria inhibition during co-culture and are found to have a promising future as epidermal wound dressing materials.

KW - antimicrobial metallics, bacterial cellulose, bandage properties, cellular and bacteria co-cultures, polymers

U2 - 10.1002/mame.201800537

DO - 10.1002/mame.201800537

M3 - Article

VL - 304

JO - Macromolecular Materials and Engineering

JF - Macromolecular Materials and Engineering

SN - 1439-2054

IS - 1

M1 - 1800537

ER -