University of Hertfordshire

Combining biology and chemistry to target the flu virus

Research output: Book/ReportBook

Standard

Combining biology and chemistry to target the flu virus. / Kukol, Andreas.

Beau Bassin : Lap Lambert Academic Publishing, 2017. 104 p.

Research output: Book/ReportBook

Harvard

Kukol, A 2017, Combining biology and chemistry to target the flu virus. Lap Lambert Academic Publishing, Beau Bassin.

APA

Kukol, A. (2017). Combining biology and chemistry to target the flu virus. Beau Bassin: Lap Lambert Academic Publishing.

Vancouver

Kukol A. Combining biology and chemistry to target the flu virus. Beau Bassin: Lap Lambert Academic Publishing, 2017. 104 p.

Author

Kukol, Andreas. / Combining biology and chemistry to target the flu virus. Beau Bassin : Lap Lambert Academic Publishing, 2017. 104 p.

Bibtex

@book{45ddb609ecbc4da8ab468db832295c94,
title = "Combining biology and chemistry to target the flu virus",
abstract = "This book presents a compilation of articles from 2009 to 2017 on the characterisation of influenza A virus proteins as drug targets. It exemplifies the strategy of combining evolutionary biological and chemical information to predict drug target sites on influenza virus proteins that are unlikely to lead to drug resistance. In addition, computational virtual screening is applied to predict potential replication inhibitors of the polymerase basic protein 2. The reader is informed about strategies to deduce protein sequence conservation from highly redundant sequences and how to combine sequence conservation with drug binding site prediction. This book is a useful resource for researchers in academia and industry starting out on drug discovery projects against pathogens with high sequence variability such as RNA viruses.",
keywords = "influenza virus, drug target, binding site, conservation",
author = "Andreas Kukol",
year = "2017",
month = "12",
day = "8",
language = "English",
isbn = "978-620-2-08100-9",
publisher = "Lap Lambert Academic Publishing",

}

RIS

TY - BOOK

T1 - Combining biology and chemistry to target the flu virus

AU - Kukol,Andreas

PY - 2017/12/8

Y1 - 2017/12/8

N2 - This book presents a compilation of articles from 2009 to 2017 on the characterisation of influenza A virus proteins as drug targets. It exemplifies the strategy of combining evolutionary biological and chemical information to predict drug target sites on influenza virus proteins that are unlikely to lead to drug resistance. In addition, computational virtual screening is applied to predict potential replication inhibitors of the polymerase basic protein 2. The reader is informed about strategies to deduce protein sequence conservation from highly redundant sequences and how to combine sequence conservation with drug binding site prediction. This book is a useful resource for researchers in academia and industry starting out on drug discovery projects against pathogens with high sequence variability such as RNA viruses.

AB - This book presents a compilation of articles from 2009 to 2017 on the characterisation of influenza A virus proteins as drug targets. It exemplifies the strategy of combining evolutionary biological and chemical information to predict drug target sites on influenza virus proteins that are unlikely to lead to drug resistance. In addition, computational virtual screening is applied to predict potential replication inhibitors of the polymerase basic protein 2. The reader is informed about strategies to deduce protein sequence conservation from highly redundant sequences and how to combine sequence conservation with drug binding site prediction. This book is a useful resource for researchers in academia and industry starting out on drug discovery projects against pathogens with high sequence variability such as RNA viruses.

KW - influenza virus

KW - drug target

KW - binding site

KW - conservation

M3 - Book

SN - 978-620-2-08100-9

BT - Combining biology and chemistry to target the flu virus

PB - Lap Lambert Academic Publishing

CY - Beau Bassin

ER -