University of Hertfordshire

Developmental evolution of dendritic morphology in a multi-compartmental neuron model

Research output: Chapter in Book/Report/Conference proceedingConference contribution


  • 901758

    Accepted author manuscript, 490 KB, PDF document

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Original languageEnglish
Title of host publicationArtificial Neural Networks
Publication statusPublished - 1999


Through the use of a multi-compartmental neuron simulation, Mainen and Sejnowski demonstrated that spike generation in neurons is a function of their dendritic structure [l]. In this paper we investigate the determination of dendritic morphology given a desired set of spike traces. A genetic algorithm is used to identify optimal parameters for a developmental model which simulates the growth of 3-dimensional dendrites. For two ’classes of ’neurons with different spiking behaviour, the developmental evolutionary process discovers ranges of viable dendritic morphologies which satisfactorally match the desired spike traces.


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