University of Hertfordshire

Haemodialysis

Research output: Contribution to journalReview article

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Original languageEnglish
Pages (from-to)478-483
Number of pages6
JournalMedicine (United Kingdom)
Volume43
Issue8
Early online date16 Jun 2015
DOIs
Publication statusPublished - 1 Aug 2015

Abstract

The haemodialysis population continues to increase and is becoming more elderly and dependent. Despite major advances in technology, long-term clinical outcomes are disappointing, even in low-risk patients. Current definitions of dialysis adequacy, based on urea clearance, need to be broadened to encompass parameters such as β 2 -microglobulin clearance, salt and water balance, and phosphate control. Haemodiafiltration provides improved β 2 -microglobulin clearance over haemodialysis, and may improve survival. There is a trend towards individualizing haemodialysis dose to the needs of the patient. Patients with significant residual kidney function may require less dialysis. For others without residual function, more frequent treatments may be necessary to adequately control uraemia and volume status, and to improve survival. Home-based treatment can facilitate more frequent treatments for a proportion of patients, although centre-based therapy remains the default for the majority.

Notes

© 2015 Elsevier Ltd. All rights reserved.

ID: 17667995