University of Hertfordshire

From the same journal

From the same journal

By the same authors

How hosts control worms

Research output: Contribution to journalComment/debate

  • M.J. Stear
  • K. Bairden
  • J.L. Duncan
  • P.H. Holmes
  • Quintin McKellar
  • M. Park
  • S. Strain
  • M. Murray
  • S.C. Bishop
  • G. Gettinby
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Original languageEnglish
Number of pages1
Pages (from-to)27
JournalNature
Journal publication date4 Sep 1997
Volume389
Issue6646
DOIs
Publication statusPublished - 4 Sep 1997

Abstract

Nematodes are a major cause of disease and death in humans, domestic animals and wildlife. Understanding why some individuals suffer severely whereas others exposed to the same infection remain healthy may assist in the development of rational and sustainable strategies to control infection. Here, using a quantitative genetic analysis of the parasitic nematode population that had accumulated naturally in lambs, we find no apparent influence of host genetics on nematode numbers but an extremely strong influence on average worm length and fecundity. Our results indicate that in growing lambs the main manifestation of genetic resistance is the control of worm fecundity

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