University of Hertfordshire

From the same journal

By the same authors

Standard

Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles : Interfacial Properties and Protein Binding. / Urbano, Laura; Clifton, Luke; Ku, Hoi Ki; Kendall-Troughton, Hannah; Vandera, Kalliopi Kelli A.; Matarese, Bruno F.E.; Abelha, Thais; Li, Peixun; Desai, Tejal; Dreiss, Cécile A.; Barker, Robert D.; Green, Mark A.; Dailey, Lea Ann; Harvey, Richard D.

In: Langmuir, Vol. 34, No. 21, 29.05.2018, p. 6125-6137.

Research output: Contribution to journalArticle

Harvard

Urbano, L, Clifton, L, Ku, HK, Kendall-Troughton, H, Vandera, KKA, Matarese, BFE, Abelha, T, Li, P, Desai, T, Dreiss, CA, Barker, RD, Green, MA, Dailey, LA & Harvey, RD 2018, 'Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles: Interfacial Properties and Protein Binding', Langmuir, vol. 34, no. 21, pp. 6125-6137. https://doi.org/10.1021/acs.langmuir.8b00561

APA

Urbano, L., Clifton, L., Ku, H. K., Kendall-Troughton, H., Vandera, K. K. A., Matarese, B. F. E., ... Harvey, R. D. (2018). Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles: Interfacial Properties and Protein Binding. Langmuir, 34(21), 6125-6137. https://doi.org/10.1021/acs.langmuir.8b00561

Vancouver

Author

Urbano, Laura ; Clifton, Luke ; Ku, Hoi Ki ; Kendall-Troughton, Hannah ; Vandera, Kalliopi Kelli A. ; Matarese, Bruno F.E. ; Abelha, Thais ; Li, Peixun ; Desai, Tejal ; Dreiss, Cécile A. ; Barker, Robert D. ; Green, Mark A. ; Dailey, Lea Ann ; Harvey, Richard D. / Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles : Interfacial Properties and Protein Binding. In: Langmuir. 2018 ; Vol. 34, No. 21. pp. 6125-6137.

Bibtex

@article{2eaab3d3bdc049a6a2269564f2dd91e4,
title = "Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles: Interfacial Properties and Protein Binding",
abstract = "π-Conjugated polymer nanoparticles (CPNs) are under investigation as photoluminescent agents for diagnostics and bioimaging. To determine whether the choice of surfactant can improve CPN properties and prevent protein adsorption, five nonionic polyethylene glycol alkyl ether surfactants were used to produce CPNs from three representative π-conjugated polymers. The surfactant structure did not influence size or yield, which was dependent on the nature of the conjugated polymer. Hydrophobic interaction chromatography, contact angle, quartz crystal microbalance, and neutron reflectivity studies were used to assess the affinity of the surfactant to the conjugated polymer surface and indicated that all surfactants were displaced by the addition of a model serum protein. In summary, CPN preparation methods which rely on surface coating of a conjugated polymer core with amphiphilic surfactants may produce systems with good yields and colloidal stability in vitro, but may be susceptible to significant surface alterations in physiological fluids.",
author = "Laura Urbano and Luke Clifton and Ku, {Hoi Ki} and Hannah Kendall-Troughton and Vandera, {Kalliopi Kelli A.} and Matarese, {Bruno F.E.} and Thais Abelha and Peixun Li and Tejal Desai and Dreiss, {C{\'e}cile A.} and Barker, {Robert D.} and Green, {Mark A.} and Dailey, {Lea Ann} and Harvey, {Richard D.}",
year = "2018",
month = "5",
day = "29",
doi = "10.1021/acs.langmuir.8b00561",
language = "English",
volume = "34",
pages = "6125--6137",
journal = "Langmuir",
issn = "0743-7463",
publisher = "American Chemical Society",
number = "21",

}

RIS

TY - JOUR

T1 - Influence of the Surfactant Structure on Photoluminescent π-Conjugated Polymer Nanoparticles

T2 - Interfacial Properties and Protein Binding

AU - Urbano, Laura

AU - Clifton, Luke

AU - Ku, Hoi Ki

AU - Kendall-Troughton, Hannah

AU - Vandera, Kalliopi Kelli A.

AU - Matarese, Bruno F.E.

AU - Abelha, Thais

AU - Li, Peixun

AU - Desai, Tejal

AU - Dreiss, Cécile A.

AU - Barker, Robert D.

AU - Green, Mark A.

AU - Dailey, Lea Ann

AU - Harvey, Richard D.

PY - 2018/5/29

Y1 - 2018/5/29

N2 - π-Conjugated polymer nanoparticles (CPNs) are under investigation as photoluminescent agents for diagnostics and bioimaging. To determine whether the choice of surfactant can improve CPN properties and prevent protein adsorption, five nonionic polyethylene glycol alkyl ether surfactants were used to produce CPNs from three representative π-conjugated polymers. The surfactant structure did not influence size or yield, which was dependent on the nature of the conjugated polymer. Hydrophobic interaction chromatography, contact angle, quartz crystal microbalance, and neutron reflectivity studies were used to assess the affinity of the surfactant to the conjugated polymer surface and indicated that all surfactants were displaced by the addition of a model serum protein. In summary, CPN preparation methods which rely on surface coating of a conjugated polymer core with amphiphilic surfactants may produce systems with good yields and colloidal stability in vitro, but may be susceptible to significant surface alterations in physiological fluids.

AB - π-Conjugated polymer nanoparticles (CPNs) are under investigation as photoluminescent agents for diagnostics and bioimaging. To determine whether the choice of surfactant can improve CPN properties and prevent protein adsorption, five nonionic polyethylene glycol alkyl ether surfactants were used to produce CPNs from three representative π-conjugated polymers. The surfactant structure did not influence size or yield, which was dependent on the nature of the conjugated polymer. Hydrophobic interaction chromatography, contact angle, quartz crystal microbalance, and neutron reflectivity studies were used to assess the affinity of the surfactant to the conjugated polymer surface and indicated that all surfactants were displaced by the addition of a model serum protein. In summary, CPN preparation methods which rely on surface coating of a conjugated polymer core with amphiphilic surfactants may produce systems with good yields and colloidal stability in vitro, but may be susceptible to significant surface alterations in physiological fluids.

UR - http://www.scopus.com/inward/record.url?scp=85046666604&partnerID=8YFLogxK

U2 - 10.1021/acs.langmuir.8b00561

DO - 10.1021/acs.langmuir.8b00561

M3 - Article

VL - 34

SP - 6125

EP - 6137

JO - Langmuir

JF - Langmuir

SN - 0743-7463

IS - 21

ER -