University of Hertfordshire

From the same journal

By the same authors

Documents

  • P40

    Final published version, 126 KB, PDF-document

View graph of relations
Original languageEnglish
Article numberP40
JournalBMC Neuroscience
Journal publication dateJul 2014
Volume15
IssueSupp 1
DOIs
StatePublished - Jul 2014

Abstract

The dendrite of the cerebellar Purkinje cell is one of the most complex structures in the mammalian brain, receiving more than 150,000 synaptic inputs. It is also one of the most extensively modelled neurons in the mammalian brain, with theoretical analysis of the input-output relationships in its dendrite extending back 40 years. While most of this experimental and modelling work has been conducted using mammalian neurons, it has also often been noted that overall cerebellar structure as well as the general morphology of Purkinje cells has been highly conserved in all vertebrate species. The work described here seeks to identify conserved features of Purkinje cell function by examining the relationship between structure and function in a range of vertebrate species from fish to mammals

Notes

Abstract from the 23rd Annual Computational Neuroscience Meeting CNS 2014. © 2014 Kidd et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated

ID: 2935887