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Lifetime Bipolar Disorder comorbidity and related clinical characteristics in patients with primary Obsessive Compulsive Disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). / Dell'Osso, Bernado; Vismara, Matteo; Benatti, Beatrice ; Cirnigliaro, Giovanna; Grancini, Benedetta; Fineberg, Naomi; Van Ameringen, Michael; Hollander, Eric; Stein, Dan J.; Menchon, Josè M; Rodriguez, Carolyn I; Nicolini, Humberto; Lanzagorta, Nuria; Pallanti, Stefano ; Grassi, Giacomo; Lochner, Christine; Marazziti, Donatella ; Hranov, Georgi; Karamustafalioglu, Oguz; Hranov, Luchezar; Zohar, Joseph.

In: CNS Spectrums, 27.05.2019.

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Dell'Osso, B, Vismara, M, Benatti, B, Cirnigliaro, G, Grancini, B, Fineberg, N, Van Ameringen, M, Hollander, E, Stein, DJ, Menchon, JM, Rodriguez, CI, Nicolini, H, Lanzagorta, N, Pallanti, S, Grassi, G, Lochner, C, Marazziti, D, Hranov, G, Karamustafalioglu, O, Hranov, L & Zohar, J 2019, 'Lifetime Bipolar Disorder comorbidity and related clinical characteristics in patients with primary Obsessive Compulsive Disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)', CNS Spectrums. https://doi.org/10.1017/S1092852919001068

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Dell'Osso, Bernado ; Vismara, Matteo ; Benatti, Beatrice ; Cirnigliaro, Giovanna ; Grancini, Benedetta ; Fineberg, Naomi ; Van Ameringen, Michael ; Hollander, Eric ; Stein, Dan J. ; Menchon, Josè M ; Rodriguez, Carolyn I ; Nicolini, Humberto ; Lanzagorta, Nuria ; Pallanti, Stefano ; Grassi, Giacomo ; Lochner, Christine ; Marazziti, Donatella ; Hranov, Georgi ; Karamustafalioglu, Oguz ; Hranov, Luchezar ; Zohar, Joseph. / Lifetime Bipolar Disorder comorbidity and related clinical characteristics in patients with primary Obsessive Compulsive Disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). In: CNS Spectrums. 2019.

Bibtex

@article{2852347c17434786aab832ad8c98ef68,
title = "Lifetime Bipolar Disorder comorbidity and related clinical characteristics in patients with primary Obsessive Compulsive Disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)",
abstract = "IntroductionBipolar disorder (BD) and obsessive compulsive disorder (OCD) are prevalent, comorbid, and disabling conditions, often characterized by early onset and chronic course. When comorbid, OCD and BD can determine a more pernicious course of illness, posing therapeutic challenges for clinicians. Available reports on prevalence and clinical characteristics of comorbidity between BD and OCD showed mixed results, likely depending on the primary diagnosis of analyzed samples.MethodsWe assessed prevalence and clinical characteristics of BD comorbidity in a large international sample of patients with primary OCD (n = 401), through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) snapshot database, by comparing OCD subjects with vs without BD comorbidity.ResultsAmong primary OCD patients, 6.2{\%} showed comorbidity with BD. OCD patients with vs without BD comorbidity more frequently had a previous hospitalization (p < 0.001) and current augmentation therapies (p < 0.001). They also showed greater severity of OCD (p < 0.001), as measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).ConclusionThese findings from a large international sample indicate that approximately 1 out of 16 patients with primary OCD may additionally have BD comorbidity along with other specific clinical characteristics, including more frequent previous hospitalizations, more complex therapeutic regimens, and a greater severity of OCD. Prospective international studies are needed to confirm our findings.",
keywords = "Bipolar disorder, comorbidity, obsessive compulsive disorder, prevalence",
author = "Bernado Dell'Osso and Matteo Vismara and Beatrice Benatti and Giovanna Cirnigliaro and Benedetta Grancini and Naomi Fineberg and {Van Ameringen}, Michael and Eric Hollander and Stein, {Dan J.} and Menchon, {Jos{\`e} M} and Rodriguez, {Carolyn I} and Humberto Nicolini and Nuria Lanzagorta and Stefano Pallanti and Giacomo Grassi and Christine Lochner and Donatella Marazziti and Georgi Hranov and Oguz Karamustafalioglu and Luchezar Hranov and Joseph Zohar",
year = "2019",
month = "5",
day = "27",
doi = "10.1017/S1092852919001068",
language = "English",
journal = "CNS Spectrums",
issn = "1092-8529",
publisher = "CAMBRIDGE UNIV PRESS",

}

RIS

TY - JOUR

T1 - Lifetime Bipolar Disorder comorbidity and related clinical characteristics in patients with primary Obsessive Compulsive Disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)

AU - Dell'Osso, Bernado

AU - Vismara, Matteo

AU - Benatti, Beatrice

AU - Cirnigliaro, Giovanna

AU - Grancini, Benedetta

AU - Fineberg, Naomi

AU - Van Ameringen, Michael

AU - Hollander, Eric

AU - Stein, Dan J.

AU - Menchon, Josè M

AU - Rodriguez, Carolyn I

AU - Nicolini, Humberto

AU - Lanzagorta, Nuria

AU - Pallanti, Stefano

AU - Grassi, Giacomo

AU - Lochner, Christine

AU - Marazziti, Donatella

AU - Hranov, Georgi

AU - Karamustafalioglu, Oguz

AU - Hranov, Luchezar

AU - Zohar, Joseph

PY - 2019/5/27

Y1 - 2019/5/27

N2 - IntroductionBipolar disorder (BD) and obsessive compulsive disorder (OCD) are prevalent, comorbid, and disabling conditions, often characterized by early onset and chronic course. When comorbid, OCD and BD can determine a more pernicious course of illness, posing therapeutic challenges for clinicians. Available reports on prevalence and clinical characteristics of comorbidity between BD and OCD showed mixed results, likely depending on the primary diagnosis of analyzed samples.MethodsWe assessed prevalence and clinical characteristics of BD comorbidity in a large international sample of patients with primary OCD (n = 401), through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) snapshot database, by comparing OCD subjects with vs without BD comorbidity.ResultsAmong primary OCD patients, 6.2% showed comorbidity with BD. OCD patients with vs without BD comorbidity more frequently had a previous hospitalization (p < 0.001) and current augmentation therapies (p < 0.001). They also showed greater severity of OCD (p < 0.001), as measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).ConclusionThese findings from a large international sample indicate that approximately 1 out of 16 patients with primary OCD may additionally have BD comorbidity along with other specific clinical characteristics, including more frequent previous hospitalizations, more complex therapeutic regimens, and a greater severity of OCD. Prospective international studies are needed to confirm our findings.

AB - IntroductionBipolar disorder (BD) and obsessive compulsive disorder (OCD) are prevalent, comorbid, and disabling conditions, often characterized by early onset and chronic course. When comorbid, OCD and BD can determine a more pernicious course of illness, posing therapeutic challenges for clinicians. Available reports on prevalence and clinical characteristics of comorbidity between BD and OCD showed mixed results, likely depending on the primary diagnosis of analyzed samples.MethodsWe assessed prevalence and clinical characteristics of BD comorbidity in a large international sample of patients with primary OCD (n = 401), through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) snapshot database, by comparing OCD subjects with vs without BD comorbidity.ResultsAmong primary OCD patients, 6.2% showed comorbidity with BD. OCD patients with vs without BD comorbidity more frequently had a previous hospitalization (p < 0.001) and current augmentation therapies (p < 0.001). They also showed greater severity of OCD (p < 0.001), as measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).ConclusionThese findings from a large international sample indicate that approximately 1 out of 16 patients with primary OCD may additionally have BD comorbidity along with other specific clinical characteristics, including more frequent previous hospitalizations, more complex therapeutic regimens, and a greater severity of OCD. Prospective international studies are needed to confirm our findings.

KW - Bipolar disorder

KW - comorbidity

KW - obsessive compulsive disorder

KW - prevalence

UR - http://www.scopus.com/inward/record.url?scp=85066908255&partnerID=8YFLogxK

U2 - 10.1017/S1092852919001068

DO - 10.1017/S1092852919001068

M3 - Article

JO - CNS Spectrums

JF - CNS Spectrums

SN - 1092-8529

ER -