University of Hertfordshire

From the same journal

By the same authors

  • Noelia Rubio
  • Rui Serra-Maia
  • Houmam Kafa
  • Kuo Ching Mei
  • Khuloud T. Al-Jamal
  • William Luckhurst
  • Mire Zloh
  • Frederic Festy
  • Jonathan P. Richardson
  • Julian R. Naglik
  • Elzbieta Pach
  • Belén Ballesteros
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Original languageEnglish
Number of pages10
Pages (from-to)14999-15008
Journal publication date16 Dec 2014
Early online date19 Nov 2014
Publication statusPublished - 16 Dec 2014


A novel, fast, and easy mechano-chemistry-based (dry milling) method has been developed to exfoliate graphene with hydrophobic drugs generating few-layer graphene mesosheets (< 10 nm in thickness and ∼1 μm in width). The electronic properties of the graphitic structure were partially preserved after the milling treatment compared with graphene oxide prepared by Hummers' method. Several characterization techniques such as thermogravimetric analysis, Raman spectroscopy, atomic force microscopy, electron microscopy, and molecular dynamics simulation were used to characterize this material. The drug-exfoliated mesosheets were pharmacologically inactive, offering a new approach for making water-soluble few-layer graphene mesosheets upon dry milling with hydrophobic drugs, mainly used as exfoliating agents. (Figure Presented).

ID: 7970432