University of Hertfordshire

From the same journal

By the same authors

Regulation of ATP production by mitochondrial Ca(2+)

Research output: Contribution to journalReview article

Standard

Regulation of ATP production by mitochondrial Ca(2+). / Tarasov, Andrei I; Griffiths, Elinor J; Rutter, Guy A.

In: Cell Calcium, Vol. 52, No. 1, 07.2012, p. 28-35.

Research output: Contribution to journalReview article

Harvard

APA

Vancouver

Author

Tarasov, Andrei I ; Griffiths, Elinor J ; Rutter, Guy A. / Regulation of ATP production by mitochondrial Ca(2+). In: Cell Calcium. 2012 ; Vol. 52, No. 1. pp. 28-35.

Bibtex

@article{ce70d71a645245c3a61babaa44b0d187,
title = "Regulation of ATP production by mitochondrial Ca(2+)",
abstract = "Stimulation of mitochondrial oxidative metabolism by Ca(2+) is now generally recognised as important for the control of cellular ATP homeostasis. Here, we review the mechanisms through which Ca(2+) regulates mitochondrial ATP synthesis. We focus on cardiac myocytes and pancreatic β-cells, where tight control of this process is likely to play an important role in the response to rapid changes in workload and to nutrient stimulation, respectively. We also describe a novel approach for imaging the Ca(2+)-dependent regulation of ATP levels dynamically in single cells.",
keywords = "Adenosine Triphosphate/biosynthesis, Calcium/metabolism, Enzymes/metabolism, Humans, Insulin-Secreting Cells/metabolism, Mitochondria/enzymology, Myocytes, Cardiac/metabolism",
author = "Tarasov, {Andrei I} and Griffiths, {Elinor J} and Rutter, {Guy A}",
note = "{\circledC} 2012 Elsevier Ltd.",
year = "2012",
month = "7",
doi = "10.1016/j.ceca.2012.03.003",
language = "English",
volume = "52",
pages = "28--35",
journal = "Cell Calcium",
issn = "0143-4160",
publisher = "Churchill Livingstone",
number = "1",

}

RIS

TY - JOUR

T1 - Regulation of ATP production by mitochondrial Ca(2+)

AU - Tarasov, Andrei I

AU - Griffiths, Elinor J

AU - Rutter, Guy A

N1 - © 2012 Elsevier Ltd.

PY - 2012/7

Y1 - 2012/7

N2 - Stimulation of mitochondrial oxidative metabolism by Ca(2+) is now generally recognised as important for the control of cellular ATP homeostasis. Here, we review the mechanisms through which Ca(2+) regulates mitochondrial ATP synthesis. We focus on cardiac myocytes and pancreatic β-cells, where tight control of this process is likely to play an important role in the response to rapid changes in workload and to nutrient stimulation, respectively. We also describe a novel approach for imaging the Ca(2+)-dependent regulation of ATP levels dynamically in single cells.

AB - Stimulation of mitochondrial oxidative metabolism by Ca(2+) is now generally recognised as important for the control of cellular ATP homeostasis. Here, we review the mechanisms through which Ca(2+) regulates mitochondrial ATP synthesis. We focus on cardiac myocytes and pancreatic β-cells, where tight control of this process is likely to play an important role in the response to rapid changes in workload and to nutrient stimulation, respectively. We also describe a novel approach for imaging the Ca(2+)-dependent regulation of ATP levels dynamically in single cells.

KW - Adenosine Triphosphate/biosynthesis

KW - Calcium/metabolism

KW - Enzymes/metabolism

KW - Humans

KW - Insulin-Secreting Cells/metabolism

KW - Mitochondria/enzymology

KW - Myocytes, Cardiac/metabolism

U2 - 10.1016/j.ceca.2012.03.003

DO - 10.1016/j.ceca.2012.03.003

M3 - Review article

VL - 52

SP - 28

EP - 35

JO - Cell Calcium

JF - Cell Calcium

SN - 0143-4160

IS - 1

ER -