University of Hertfordshire

Using randomised vectors in transcription factor binding site predictions

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Original languageEnglish
Title of host publicationProcs of 9th Int Conference on Machine Learning and Applications, ICMLA
PublisherIEEE
Pages523-527
ISBN (Print)978-1-4244-9211-4
DOIs
Publication statusPublished - 2010

Abstract

Finding the location of binding sites in DNA is a difficult problem. Although the location of some binding sites have been experimentally identified, other parts of the genome may or may not contain binding sites. This poses problems with negative data in a trainable classifier. Here we show that using randomized negative data gives a large boost in classifier performance when compared to the original labeled data.

Notes

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