Projects per year
Organisation profile
Organisation profile
The Centre for Research in Mechanisms of Disease and Drug Discovery has a focus on fundamental life sciences applied to the understanding of human health and disease, and the development of novel therapeutic approaches with potential to translate to the clinical setting.
The Centre provides a vibrant, multidisciplinary environment that brings together scientific researchers with expertise in the biological, pharmacological and chemical sciences, to develop novel approaches to tackling some of the major global health and therapeutic challenges.
Research covers a broad range of health-related areas, including genetic diseases, mechanisms of cancer and targets for novel therapies, infectious diseases and antimicrobial resistance, and chronic, inflammatory and neurodegenerative conditions.
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Collaborations and top research areas from the last five years
Profiles
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KTP: Human Facial Expression Identification using AI for Clinical Trials
Helian, N. (PI) & Lione, L. (CoPI)
2/03/26 → 1/02/29
Project: Research
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In Silico Design and Synthetic Planning of Novel METTL3 Inhibitors for High- Risk Neuroblastoma
Ostovar, M. (PI), Rossiter, S. (CoI) & Botha, M. (CoI)
5/01/26 → 4/01/27
Project: Research
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Co-Producing Parkinson’s Research Engagement Events
Hadley, R. (PI), Annett, L. (CoI), Iravani, M. (CoI), Yousif, N. (CoI) & Herman, R. (CoI)
UKRI - Economic and Social Research Council (ESRC)
6/05/25 → 30/11/26
Project: Research
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RESPIRATORY BIOMARKERS: AN OPPORTUNITY FOR PATIENT-CENTRIC MICROSAMPLING APPROACH FOR TREATMENT OPTIMIZATION
Khan, A., Stair, J., Baker, D., Spooner, N. & Murnane, D., 30 Jun 2026, In: Clinical and Translational Science. 19, 6, 22 p., e70600.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
NLX-112, a selective 5 HT1A receptor agonist, upregulates GDNF and is neuroprotective against MPTP-induced nigrostriatal degeneration in a mouse model of Parkinson’s disease
Powell, W., Annett, L., Depoortere, R., Newman-Tancredi, A. & Iravani, M. M., 25 Jun 2026, (Accepted/In press) In: ACS chemical neuroscience. MSC cn-2026-00251g.Research output: Contribution to journal › Article › peer-review
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Crawling into the Unknown: Unveiling Novel Psychoactive Substances (NPSs) in the post pandemic era utilizing the NPSfinder®
Deligianni, E., Vento, A., Papazisis, G., Goulas, A., Lione, L. & Schifano, F., 22 Jun 2026, (Accepted/In press) In: International Journal of Toxicology. UITO-2025-0647-R3.Research output: Contribution to journal › Article › peer-review