Centre for Research in Mechanisms of Disease and Drug Discovery

Organisation profile

Organisation profile

The Centre for Research in Mechanisms of Disease and Drug Discovery has a focus on fundamental life sciences applied to the understanding of human health and disease, and the development of novel therapeutic approaches with potential to translate to the clinical setting.

The Centre provides a vibrant, multidisciplinary environment that brings together scientific researchers with expertise in the biological, pharmacological and chemical sciences, to develop novel approaches to tackling some of the major global health and therapeutic challenges.

Research covers a broad range of health-related areas, including genetic  diseases, mechanisms of cancer and targets for novel therapies, infectious diseases and antimicrobial resistance, and chronic, inflammatory and neurodegenerative conditions.

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Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Adhesion G protein-coupled receptors

    Formstone, C., Langenhan, T., Anderson, G., Araç, D., Aust, G., Avila-Zozaya, M., Bagger, S. M., Barth, P., Berndt, S., Blacklow, S. C., Blanco-Redondo, B., Boucard, A. A., Bridges, J., Brodmerkel, L.-S., Caron, K. M., Chung, Y. K., Dates, A. N., de Araujo Farias, V., Del Toro, D. & Duman, , J. G. & 63 others, Engel, F. B., Favara, D. M., Fu, C., De Las Bayonas, A. G., Georgiadi, A., Gloriam, D. E., Hall, R. A., Hamann, J., Hildebrand, P. W., Hsiao, C.-C., Huang, B. X., Javitch, J. A., Kim, H.-Y., Kittel, R. J., Kleinau, G., Leduc, R., Liebscher, I., Lin, H.-H., Linnert, J., Ludwig, M.-G., Martinelli, D. C., Mathiasen, S., Matúš, D., Melkumyan, M., Moreno-Salinas, A. L., Mulder, J., Nash, M. A., Pal, K., Pederick, D. T., Perry-Hauser, N. A., Piao, X., Ping, Y.-Q., Placantonakis, D. G., Pohl, F., Prömel, S., Rosenkilde, M. M., Sabbagh, L., Sando, R. C., Scheerer, P., Schöneberg, T., Seiradake,, E., Selcho, M., Seufert, F., Singh, A. K., Skiniotis, G., Spiess, K., Sträter, N., Strutt, D., Südhof, T. C., Sun, J., Tall, G. G., Thor, D., Tilley, D. G., Tolias, K. F., Vallon, M., Van Meir, E. G., Vanhollebeke, B., Wiggin, G. R., Wolfrum, U., Yan, J., Zaidman, N. A., Zou, Y. & Scholz, N., 15 Jan 2026, In: Pharmacological reviews.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
  • A novel, PCP-dependent tissue organising principle coordinating morphogenesis between embryonic skin epidermal layers

    Formstone, C. J., 8 Jan 2026, (E-pub ahead of print) In: Journal of Anatomy. 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
  • In silico investigation of novel Plasmodium Falciparum glycogen synthase kinase (pfGSk3β) inhibitors for the treatment of malaria infection

    Adebambo, K. & Otify, S., 8 Dec 2025, PLoS ONE, 20, 12 26 p.

    Research output: Contribution to specialist publicationArticle

    Open Access
    File