Centre for Research in Mechanisms of Disease and Drug Discovery

Research output

Research output per year 1982 2005 2009 2011 2013 2014 2015 2016 2017 2020 2021 2023 2024

• 570 Article
• 39 Review article
• 30 Conference contribution
• 29 Poster
• 138 More
  • 28 Meeting abstract
  • 18 Special issue
  • 16 Chapter (peer-reviewed)
  • 15 Abstract
  • 8 Editorial
  • 8 Literature review
  • 8 Patent
  • 7 Presentation
  • 6 Doctoral Thesis
  • 5 Book
  • 4 Chapter
  • 4 Letter
  • 3 Working paper
  • 2 Paper
  • 2 Comment/debate
  • 2 Master's Thesis
  • 1 Other
  • 1 Other contribution

Research output per year

Research output per year

Search results

• 2018

  Kv7 channel regulation of colonic motility in mice

  Keating, C., Hassan, A.-A. & Iravani, M., 2018, In: Neurogastroenterology and Motility. 30, S1

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  • Motor Complex 100%
  • Colonic Motility 100%
  • Kv7 Channels 100%
  • Channel Regulation 100%
  • Colon Motility 100%
• 2017

  Anti-Inflammatory Activity of Novel Trans-Stilbene Sulfonamide Analogues as Potential Novel Therapeutic Agents for Lung Disease

  Mahendran, R., Osoba, E., Rossiter, S., Bassin, J., Cook, M. & Hutter, V., 1 Aug 2017, In: Journal of Aerosol Medicine and Pulmonary Drug Delivery. 29, 3, p. A21 65.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access
  1 Citation (Scopus)
• 2016

  TRPA1 channel activation regulates motility in the mouse colon

  Sleet, B. & Keating, C., 2016, In: pA2 online. 13, 3, 303P.

  Research output: Contribution to journal › Meeting abstract › peer-review

• 2015

  Study of the mechanisms contributing to visceral hypersensitivity in a rat model of acute and postinflammatory colitis: focus on splanchnic afferent nerve signaling

  Deiteren, A., de Man, J. D. M., Keating, C., Jiang, W., Pelckmans, P. & de Winter, B., Jun 2015, In: Neurogastroenterology and Motility. 27, S2, p. 53-54

  Research output: Contribution to journal › Meeting abstract › peer-review

• The effect of prolonged CLP-induced sepsis on jejunal mesenteric afferent nerve activity in mice

  Nullens, S., Deiteren, A., de Man, J., Keating, C., Jiang, W., Grundy, D. & de Winter, B., Jun 2015, In: Neurogastroenterology and Motility. 27, S2, p. 22 001.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse

  Keating, C. & Grundy, D., 2015, In: pA2 online. 21, 3, 258P.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

  File

  • Mechanosensory 100%
  • Aged Mice 100%
  • Chemosensory Function 100%
  • Sensory Function 100%
  • Aging 100%
  47 Downloads (Pure)

• A technique to enhance the desiccation tolerance of mammalian cells: exploitation of novel proteins from Deinococcus radiodurans

  Tundidor, I., Patel, P. & Chau, D., 2015, In: European Cells and Materials (ECM).

  Research output: Contribution to journal › Meeting abstract › peer-review

• ELISA screen of novel compounds that inhibit S100P and RAGE binding to identify new candidate drugs as a new therapy for pancreatic cancer.

  Ogbeni, D., Camara, R., Chau, D., Kirton, S., Patel, P., MacKenzie, L. & Rossiter, S., 2015, In: pA2 online. 13, 3, 256P.

  Research output: Contribution to journal › Meeting abstract › peer-review

  Open Access

• The streptozocin model of diabetes induces neuropathic pain, anhedonia and impaired burrowing in rats

  Lione, L., 2015, In: pA2 online. 13, 3, 1 p., abst 252P.

  Research output: Contribution to journal › Meeting abstract

  Open Access

  File

  • Burrow 100%
  • Neuropathic Pain 100%
  • Streptozotocin 100%
  • Anhedonia 100%
  • Diabetes 100%
  38 Downloads (Pure)
• 2014

  Physiological and Functional Changes in the Colon of MPTP-Treated Common Marmosets

  Coletto, E., Tough, I., Hikima, A., Iravani, M. M., Chaudhuri, K. R., Jenner, P., Cox, H. & Rose, S., May 2014, In: Movement disorders. 29, Suppl 1, 1525.

  Research output: Contribution to journal › Meeting abstract

  • Physiological Changes 100%
  • Common Marmoset 100%
  • Functional Change 100%
  • Colon 100%
  • 1,2,3,6 Tetrahydro 1 Methyl 4 Phenylpyridine 100%
• 2013

  The spontaneous and neurogenic contractile responses of the isolated bladder smooth muscle are markedly enhanced in MPTP treated common marmoset (Callithrix jacchus)

  Pritchard, S., Jackson, M., Lione, L., Benham, C., Rose, S., Jenner, P. & Iravani, M. M., Dec 2013, In: pA2 online. 11, 3, 208P.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Contractile Response 100%
  • Bladder Smooth muscle 100%
  • Common Marmoset 100%
  • 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 100%
  • Callithrix Jacchus 100%

• Increase in the number of striatal neuronal nitric oxide synthase immunoreactive (nNOS-ir) interneurones in MPTP-treated common marmosets primed for and displaying levodopa-induced dyskinesia

  Peeris, M., Geraldes, L., Jackson, M., Hikima, A., Broadstock, M., Rose, S., Jenner, P. & Iravani, M. M., 2013, In: pA2 online. 11, 3, 2 p., 219P.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Common Marmoset 100%
  • Interneuron 100%
  • Neuronal Nitric Oxide Synthase (nNOS) 100%
  • Levodopa-induced Dyskinesia 100%
  • Dyskinesia 100%
• 2012

  A comparison of novel N(G),N(G)-disubstituted arginines on recombinant dimethylarginine dimethylaminohydrolase-1 activity and nitrite production in RAW264.7 macrophages

  Morfill, C., Rossiter, S. & Smith, C., 2012, In: pA2 online. 10, 4, 197P.

  Research output: Contribution to journal › Meeting abstract
• 2009

  Post-infectious visceral hypersensitivity persists in the TRPV1 knockout mouse

  Keating, C. & Grundy, D., May 2009, In: Gastroenterology. 136, 5 (Supp 1), p. A-75

  Research output: Contribution to journal › Meeting abstract
• 2008

  Continuous vs pulsatile administration of rotigotine in rat and monkey models of Parkinson's disease: A comparison

  Scheller, D. K. A., Schmidt, W. J., Jackson, M. J., Ruess, U., Stockwell, K., Heindl, M., Iravani, M. M., Tayarani-Binazir, K., Rose, S. & Jenner, P., 2008, In: Movement disorders. 23, Supp 1, p. S86 1 p., 249.

  Research output: Contribution to journal › Meeting abstract › peer-review

• 2004

  The effects of pallidotomy on motor function in MPTP-treated, L-DOPA primed common marmosets

  Costa, S. S., Iravani, M. M., Jackson, M. J. & Jenner, P., 2004, In: Movement disorders. 19, Supp 9, p. S319 1 p., P927.

  Research output: Contribution to journal › Meeting abstract › peer-review

• 2002

  Ecstasy (3,4-Methylenedioxymethamphetamine) inhibits dyskinesia expression and normalises locomotor activity in parkinsonian primates

  Iravani, M. M., Jackson, M. J., Al-Barghouthy, G., Kouppamaki, M. & Jenner, P., 2002, In: Movement disorders. 17, Supp 5, p. S62 1 p., P163.

  Research output: Contribution to journal › Meeting abstract › peer-review

• The effect of unilateral pallidotomy on motor disability, and L-dopa-induced dyskinesia in parkinsonian marmosets

  Iravani, M. M., Costa, S., Jackson, M. J., Al-Bargouthy, G. & Jenner, P., 2002, In: Movement disorders. 17, Supp 5, p. S93 1 p., P265.

  Research output: Contribution to journal › Meeting abstract › peer-review

• 1995

  Heterogeneous effects of NMDA on dopamine release in the rat caudate-putamen

  Iravani, M. M. & Kruk, Z. L., Jul 1995, In: British Journal of Pharmacology. 115, Supp 1, p. P113 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Effects of 6-Hydroxydopamine lesions in the ventral tegmental area or substantia-nigra on dopamine release in subregions of the rat striatum

  Iravani, M. M., Khan, S., Michaeltitus, A., Whelpton, R. & Kruk, Z. L., Apr 1995, In: British Journal of Pharmacology. 114, Supp 1, p. P337 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
• 1994

  NMDA releases a nitric oxide-like substance in rat striatum: a study using fast cyclic voltammetry

  Iravani, M. M., Millar, J. & Kruk, Z. L., Jul 1994, In: British Journal of Pharmacology. 112, p. U101 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• 1992

  Effect of NMDA receptor blockade on dopamine overflow in rat caudate putamen

  Iravani, M. M. & Kruk, Z. L., Dec 1992, In: British Journal of Pharmacology. 107, Supp 2, p. P341 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review
  31 Citations (Scopus)

• Differential sensitivities of rat striatal D-2 Dopamine autoreceptor sites

  Iravani, M. M. & Kruk, Z. L., Oct 1992, In: British Journal of Pharmacology. 107, Supp 1, p. P214 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Dopamine releasing actions of NMDA in rat caudate putamen studied by fast cyclic voltammetry

  Iravani, M. M. & Kruk, Z. L., Jul 1992, In: British Journal of Pharmacology. 106, Supp 1, p. 122P 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Dopamine 100%
  • Fast-scan Cyclic Voltammetry 100%
  • Caudate-putamen 100%
  • N-Methyl-D-Aspartic Acid 100%
  • Putamen 100%
• 1988

  Evidence for neuropeptide-Y (NPY) as the probable non-cholinergic motor transmitter in rat urinary-bladder in vitro

  Iravani, M. M. & Zar, M. A., Sept 1988, In: Journal of Physiology. 403, Supp, p. 61P 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Inhibition of non-cholinergic motor transmission in isolated rat urinary-bladder by nifedipine

  Iravani, M. M., Luheshi, G. N. & Zar, M. A., Jul 1988, In: Journal of Physiology. 401, Supp, p. 69P 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• 1987

  Effect of frequency of stimulation on neurogenic responses of isolated rat epidymal vas deferens

  Iravani, M. M. & Zar, M. A., Dec 1987, In: Journal of Physiology. 391, Supp, p. P50 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

• Occurrence and distribution of neuropeptide Y (NPY)-immunoreactive nerves in rat isolated anococcygeus, and the effect of NPY on the inhibitory transmission

  Iravani, M. M., McDermott, J. R., Turner, J. D. & Zar, M. A., Oct 1987, In: Journal of Physiology. 391, Supp, p. 112P 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review