Projects per year
Organization profile
The Research Centre in Topical Drug Delivery and Toxicology (TDDT), led by Dr William McAuley, is an internationally renowned Centre of Excellence in the field of the development of in ex corporem models for the study of xenobiotic sorption with 2 main areas of application:
- developing and/or refinement of topical and transdermal formulations and
- reducing the risk of CBRN (chemical, biological, radiological and nuclear) exposure through emergency response procedures.
Research themes being developed include:
- topical formulations with a lower risk of systemic toxicity especially for paediatrics and the elderly
- development of mucosal drug delivery systems
- evaluating the application of pupilometry for the diagnosis of acute head injury or chronic diseases
- the development of sebomics for non-invasive diagnostics, forensic and environmental biomonitoring, and
- the development of microsampling science for high-sensitivity bioanalysis to determine drug and CBRN exposure in various matrices.
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Profiles
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31 March 2023: Identification, selection, characterization and optimisation of antimicrobial proteins from food insects and indigenous chickens’ skin and feathers as ingredients for food and industrial applications
Ren, G., Timms, A., Fitt, B., Stair, J., Oloo, B., Nduko, J., Ogendo, J. & Mungai, N.
1/10/22 → …
Project: Research
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Digital Microfluidic Lab-on-a-chip for multiplex detection of biomarkers in exhaled breath
Coudron, L., Urbano, L. & Johnston, I.
1/09/22 → 30/09/26
Project: Research
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Investigation Into Analytical Workflows for Microsampling Technologies
Baker, D., Neil, S., Hannam, S. & Murnane, D.
Capitainer AB, Hertfordshire Science Partnership (HSP)
1/08/22 → 31/07/23
Project: Research
Research output
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Incorporating New Approach Methodologies into Regulatory Nonclinical Pharmaceutical Safety Assessment
Hutter, V., Pound, P., Turner, J., Owen, C., Hutchinson, I., Hop, M., Chau, D., Barrios Silva, L., Coleman, M., Dubourg, A., Kenna, G., Lauschke, V., Neuhaus, W., Roper, C., Watkins, P., Welch, J., Taylor, K., Alvarez, L. & Harries, L., Jan 2023, In: ALTEX.Research output: Contribution to journal › Article › peer-review
Open Access -
In situ gelling drug delivery systems for topical drug delivery
Cook, M. T. & Kolawole, O., 11 Jan 2023, (Accepted/In press) In: European Journal of Pharmaceutics and Biopharmaceutics.Research output: Contribution to journal › Article › peer-review
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Serendipitous Enhancement of the Dimensionality in Diketopyrrolopyrroles through O-Substitution
Warzecha, M., Kennedy, A. R., McHugh, C. J. & Calvo-Castro, J., 20 Jan 2023, In: Crystal Growth & Design.Research output: Contribution to journal › Article › peer-review