Projects per year
Organisation profile
Organisation profile
The Research Centre in Topical Drug Delivery and Toxicology (TDDT), led by Dr William McAuley, is an internationally renowned Centre of Excellence in the field of the development of in ex corporem models for the study of xenobiotic sorption with 2 main areas of application:
- developing and/or refinement of topical and transdermal formulations and
- reducing the risk of CBRN (chemical, biological, radiological and nuclear) exposure through emergency response procedures.
Research themes being developed include:
- topical formulations with a lower risk of systemic toxicity especially for paediatrics and the elderly
- development of mucosal drug delivery systems
- evaluating the application of pupilometry for the diagnosis of acute head injury or chronic diseases
- the development of sebomics for non-invasive diagnostics, forensic and environmental biomonitoring, and
- the development of microsampling science for high-sensitivity bioanalysis to determine drug and CBRN exposure in various matrices.
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Collaborations and top research areas from the last five years
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Profiles
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RSC Researcher Development and Travel Grant
Hajirasouliha, F. (PI)
18/11/24 → 22/01/25
Project: Research
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Development and Characterization of a Duckweed-Based Biostimulant (DWEBS) for Enhanced Crop Growth and Stress Resistance
Barrero Sicilia, C. (PI) & Stair, J. (CoI)
9/09/24 → 8/09/25
Project: Research
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Mechanistic insight into heat enhanced permeation of diclofenac and piroxicam in combination with chemical penetration enhancers across skin
Caserta, F., Brown, M. B. & McAuley, L., 1 Dec 2024, In: European Journal of Pharmaceutical Sciences. 203, 10 p., 106933.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Evaluation of emergency skin decontamination protocols in response to an acid attack (vitreolage)
Matar, H., Vuddanda, P. & Chilcott, R., 30 Nov 2024, In: Burns. 50, 8, p. 1968-1976 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)
Sharma, M., Huber, E., Arnesdotter, E., Behrsing, H. P., Bettmann, A., Brandwein, D., Constant, S., Date, R., Deshpande, A., Fabian, E., Gupta, A., Gutierrez, R., Gutleb, A. C., Hargrove, M. M., Hollings, M., Hutter, V., Jarabek, A. M., Kaluzhny, Y., Landsiedel, R. & Milchak, L. & 16 others, , 4 Oct 2024, (E-pub ahead of print) In: Archives of Toxicology. 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure)