Centre for Research into Topical Drug Delivery and Toxicology

Projects

Projects per year 2007 2010 2011 2012 2014 2017 2018 2026

• 7 Active
• 14 Not started
• 111 Finished

Projects per year

Search results

• Finished

  Investigation Into Analytical Workflows for Microsampling Technologies

  Baker, D., Neil, S., Hannam, S. & Murnane, D.

  Capitainer AB, Hertfordshire Science Partnership (HSP)

  1/08/22 → 31/07/23

  Project: Research

• KEEP+ BETAR

  Wu, H., Johnston, I. & Cook, M. T.

  1/02/22 → 31/01/23

  Project: Research

  • regional development 100%
  • project 46%

• Fast-Track Project - ImmuOne

  Cook, M. T., Hutter, V. & Hoffman, E.

  1/09/21 → 31/08/22

  Project: Research

• Undergraduate Research Bursary - Thermothickening Engineered Emulsions

  Cook, M. T.

  31/05/21 → 23/07/21

  Project: Research

• Antiviral-QAuCuNPs: Creation of gold nanocluster modified copper nanoparticles in colloids to enhance their antiviral performance against coronaviruses including COVID-19

  Ren, G., Ryan, S., Gorog, D., Stair, J. & Timms, A.

  3/05/21 → 2/05/23

  Project: Research

  • Gold Nanoclusters 100%
  • Nanoclusters 77%
  • Colloids 64%
  • Viruses 52%
  • nanoclusters 49%

• Evaluation of tablet quality for veterinary use

  Liu, F., Stair, J., Scott, M. & Baker, D.

  1/01/21 → 1/07/21

  Project: Research

  • packaging 100%
  • assays 61%
  • sampling 40%

• National Core Study: Covid Transmission - Bioaerosol Instrumentation Design

  Murnane, D., Dimov, N. & Johnston, I.

  1/12/20 → 31/03/21

  Project: Research

  • Specifications 100%
  • Aerosols 93%
  • Microorganisms 92%
  • Fluid dynamics 81%

• Engineering thermoresponsive materials via supracolloidal assembly in polymer-stabilised emulsions.

  Cook, M. T. & Dreiss, C. A.

  1/05/20 → 6/09/21

  Project: Research

  • Gelator 100%
  • Critical Solution Temperature 89%
  • routes 67%
  • Polymers 59%
  • polymers 47%

• Impact of lifestyle on skin barrier health

  McAuley, L., Kass, L. & Raj, N.

  1/10/19 → 30/09/23

  Project: Other

  • Lifestyle 100%
  • Health 71%

• Conjugated polymer nanoparticles for imaging and theranostic applications

  Urbano, L.

  17/06/19 → 9/08/19

  Project: Other

• Smart polymers to replace antibodies in diagnostic testing

  Cook, M. T.

  14/06/19 → 9/08/19

  Project: Other

  • Stimuli Responsive Polymers 100%
  • HIV 58%
  • Temperature 40%
  • Antibodies 31%
  • Libraries 25%

• Development of in vitro co-culture model for ophthalmic drug toxicity testing.

  Hoffman, E. & Hutter, V.

  20/05/19 → 14/07/19

  Project: Other

  • eyes 100%
  • safety testing 68%
  • drug toxicity 59%
  • coculture 46%
  • college students 46%

• Cobalt Skin testing

  Matar, H. & Chilcott, R.

  1/05/19 → 1/09/19

  Project: Other

• Thermoresponsive antiviral polymers

  Cook, M. T.

  7/01/19 → 7/01/20

  Project: Other

  • polymers 100%

• Development of microparticles for patients with dysphagia

  Liu, F.

  1/12/18 → 31/05/19

  Project: Other

  • Organized Financing 100%
  • Deglutition Disorders 85%

• Medecins Sans Frontieres study

  Chilcott, R. & Matar, H.

  26/11/18 → 30/11/18

  Project: Other

  • ergonomics 100%
  • chemical 37%
  • test 29%

• Contract research studies for MedPharm

  Larner, J. & Chilcott, R.

  1/11/18 → 31/01/19

  Project: Research

  • research projects 100%

• A comparative study of the use and impact of cognitive enhancers within Higher Education in the UK and UAE

  Guirguis, A., Fergus, S. & Schifano, F.

  1/10/18 → 30/09/21

  Project: Research

• Demystifying Academic Expectations: supporting academic transition into and through a programme of study

  Fergus, S.

  28/09/18 → 2/09/19

  Project: Research

  • program of study 100%
  • education 51%
  • student 41%
  • evaluation 38%
  • resources 36%

• Drug Inhalation Response Challenge

  Hutter, V. & Martin, A.

  17/09/18 → 7/03/19

  Project: Other

  • Lung 100%
  • Inhalation Administration 40%
  • Asbestos 31%
  • Safety 31%
  • Aerosols 28%

• Development of forensic methodologies for the in-field identification of opioids (prescription & designer) using Raman spectroscopic and chemometric approaches

  Guirguis, A., Stair, J. & Kirton, S.

  17/09/18 → 16/09/22

  Project: Other

  • Prescription 100%
  • Designer 90%
  • Knowledge Exchange 85%
  • Methodology 38%

• Development of in vitro co-culture model for pulmonary fibrosis.

  Hoffman, E. & Chau, D.

  2/07/18 → 17/08/18

  Project: Other

  • Lung 100%
  • Fibrosis 92%
  • Pulmonary Fibrosis 71%
  • In Vitro Techniques 40%
  • Coculture Techniques 31%

• Microautoradiography study with flurbiprofen

  Larner, J.

  15/05/18 → 14/06/18

  Project: Other

  • Tissue 100%

• Ligand-protein studies for development of inhibitors of S100P, as a potential novel therapy for pancreatic cancer

  Rossiter, S., Kirton, S. & Hyvönen, M.

  1/04/18 → 31/12/19

  Project: Other

  • Cancer 100%
  • Research Collaboration 67%
  • Therapy 66%
  • Hertfordshire 62%
  • Accelerator 58%

• KTP - Valve design optimisation

  Murnane, D. & Kirton, S.

  1/03/18 → 28/02/21

  Project: Other

  • Product development 100%
  • Chemical analysis 64%
  • Mechanical engineering 52%
  • Product design 46%
  • Engineers 33%

• Assessing Knowledge and Enhancing Detection of Seized Psychoactive Substances in Prisons

  Guirguis, A., Stair, J. & Kirton, S.

  1/02/18 → 31/01/21

  Project: Research

• Bifunctional complexes with bronchodilator and anti-inflammatory activity

  Murnane, D., Cook, M. T. & Page, C.

  2/01/18 → 31/12/19

  Project: Other

  • Bronchodilator Agents 100%
  • Bronchoconstriction 80%
  • Anti-Inflammatory Agents 64%
  • Lead 60%
  • Chronic Obstructive Pulmonary Disease 58%

• Development of microparticle formulations for dysphagia patients

  Liu, F. & Murnane, D.

  1/01/18 → 1/01/22

  Project: Other

• Ligand-protein studies for development of inhibitors of S100P

  Rossiter, S., Kirton, S. & Hyvönen, M.

  1/01/18 → 31/12/19

  Project: Research

• Thermogelling emulsions for topical drug delivery

  Cook, M. T.

  1/12/17 → 31/10/17

  Project: Other

  • emulsions 100%
  • drugs 74%
  • delivery 70%
  • copolymers 55%
  • prophylaxis 49%

• Development and Characterisation of Novel, Inter-connected, Microphysical Systems (MPS) of Human Organs

  Chau, D., Hutter, V., Murnane, D. & Hoffman, E.

  1/10/17 → 30/09/21

  Project: Other

• Characterising in vitro airway responses to inhaled particulates

  Hutter, V., Murnane, D. & Hoffman, E.

  31/07/17 → 8/09/17

  Project: Other

  • Respiratory Therapy 100%
  • Cystic Fibrosis 71%
  • Drug Development 69%
  • Chronic Obstructive Pulmonary Disease 65%
  • In Vitro Techniques 64%

• Evaluating the response of alveolar macrophages to inhaled medicines

  Hutter, V. & Hoffman, E.

  17/07/17 → 8/09/17

  Project: Other

  • Alveolar Macrophages 100%
  • Emphysema 40%
  • Lung 38%
  • Drug Development 34%
  • Rodentia 29%

• AFR2017: Development of human in vitro model for respiratory diseases investigation

  Hoffman, E.

  3/07/17 → 25/08/17

  Project: Other

  • Human Development 100%
  • Pharmaceutical Preparations 57%
  • Alveolar Epithelial Cells 52%
  • Alveolar Macrophages 51%
  • In Vitro Techniques 50%

• Prediction of Cytochrome P450 2D6 interaction from atomic structure

  Kirton, S.

  3/07/17 → 25/08/17

  Project: Other

  • Cytochrome P-450 Enzyme System 100%

• Thermogelling materials for the improved vaginal retention of bioactives

  Cook, M. T.

  3/07/17 → 25/08/17

  Project: Other

  • HIV 100%
  • Barrier Contraception 60%
  • Pre-Exposure Prophylaxis 51%
  • Africa South of the Sahara 40%
  • Anti-Infective Agents 37%

• Pasta la vista: a potential biomaterial for regenerative medicine

  Chau, D.

  5/06/17 → 30/07/17

  Project: Other

  • pasta 100%
  • biocompatible materials 56%
  • medicine 53%
  • animal research 31%
  • wheat protein 29%

• UKICRS Summer Studentship - Thermogelling emulsions for topical drug delivery

  Cook, M. T.

  15/05/17 → 7/07/17

  Project: Other

  • emulsions 100%
  • copolymers 95%
  • surfactants 93%
  • drugs 86%
  • delivery 82%

• Investigating the impact of macrophage polarization on foamy macrophage response in vitro.

  Hoffman, E.

  1/03/17 → 31/10/17

  Project: Research

  File

  • Macrophages 100%
  • Alveolar Macrophages 79%
  • Clinical Studies 49%
  • In Vitro Techniques 31%

• KHN Consortium Crack IT challenge 14: Inhalation translation

  Hutter, V. & Murnane, D.

  UKRI - The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs)

  1/02/17 → 29/11/18

  Project: Other

  • Inhalation 100%

• Development of an invertebrate model (Galleria mellonella) for drug screening and toxicity testing

  Hall, C.

  9/01/17 → 31/07/17

  Project: Research

  • Preclinical Drug Evaluations 100%
  • Drug-Related Side Effects and Adverse Reactions 77%
  • Moths 59%
  • Waxes 53%
  • Invertebrates 48%

• INFORM 2020 – Molecules to Manufacture: Processing and Formulation Engineering of Inhalable Nanoaggregates and Microparticles

  Murnane, D., Hutter, V. & Chau, D.

  3/10/16 → 30/01/21

  Project: Other

  • Aerosols 100%
  • Powders 81%
  • Terbutaline Sulfate 61%
  • Inhalation 53%
  • lactose 50%

• Thermogelling materials for intravaginal drug delivery

  Cook, M. T.

  1/10/16 → 30/09/17

  Project: Other

  • drugs 100%
  • body temperature 96%
  • delivery 94%
  • block copolymers 79%
  • Poloxamer 75%

• Occoris - Self Activating Smart Inhaler

  Murnane, D. & Hutter, V.

  UKRI - Engineering and Physical Sciences Research Council (EPSRC)

  1/10/16 → 31/05/18

  Project: Other

  • smart materials 100%
  • aerosols 37%
  • engineering 27%
  • products 23%
  • fabrication 22%

• Summer Studentship Project ‐ Development of an in silico database to predict the safety of new medicines for respiratory disease in humans

  Hutter, V.

  11/07/16 → 2/09/16

  Project: Other

  • Pulmonary Medicine 100%
  • Decision Trees 89%
  • Computer Simulation 73%
  • Safety 72%
  • Immune System 57%

• Development of novel formulations for older adults

  Liu, F.

  Fluid Pharma Ltd

  1/07/16 → 31/05/19

  Project: Other

• Evaluation of a topical anti-oxidative formula.

  Chilcott, R. & Traynor, M.

  1/07/16 → 30/09/16

  Project: Other

  • Antioxidants 100%
  • Clinical Trials 87%

• Biomedical Vacation Scholarship, Assessing alveolar macrophage responses to inhaled medicines

  Hutter, V.

  20/06/16 → 30/09/16

  Project: Other

  • Alveolar Macrophages 100%
  • Lung Diseases 96%
  • Chronic Obstructive Pulmonary Disease 64%
  • Safety 63%
  • Lung 57%

• Investigation into percutaneous absorption of fusidic acid in canine skin

  Larner, J.

  1/03/15 → 31/05/15

  Project: Research

• Development of a Tissue Engineered Atherosclerosis Controlled Host (TEACH) Model

  Ruiz Hincapie, P., Chau, D., Hutter, V., Ihracska, A. B. & Ruiz, L. M.

  18/02/15 → 18/09/17

  Project: Research