Research output per year
Research output per year
- 15 results
Search results
-
2023
A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models
Hoolachan, J. M., McCallion, E., Sutton, E. R., Çetin, Ö., Pacheco-Torres, P., Dimitriadi, M., Sari, S., Miller, G. J., Okoh, M., Walter, L. M., Claus, P., Wood, M. J. A., Tonge, D. P. & Bowerman, M., 8 Nov 2023, In: Human molecular genetics. p. 1-26 26 p., ddad192.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Downloads (Pure) -
2020
Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy
Walsh, M. B., Janzen, E., Wingrove, E., Hosseinibarkooie, S., Rodriguez Muela, N., Davidow, L., Dimitriadi, M., M. Norabuena, E., L Rubin, L., Wirth, B. & C. Hart, A., 16 Sept 2020, In: BMC Biology. 18, 1, 19 p., 127.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)41 Downloads (Pure) -
2018
Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration
Baskoylu, S. N., Yersak, J., O'Hern, P., Grosser, S., Simon, J., Kim, S., Schuch, K., Dimitriadi, M., Yanagi, K. S., Lins, J. & Hart, A. C., 8 Oct 2018, In: PLoS Genetics. 14, 10, p. e1007682 e1007682.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)61 Downloads (Pure) -
2017
PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation
Gupta, A., Anjomani-Virmouni, S., Koundouros, N., Dimitriadi, M., Choo-Wing, R., Valle, A., Zheng, Y., Chiu, Y-H., Agnihotri, S., Zadeh, G., Asara, J. M., Anastasiou, D., Arends, M. J., Cantley, L. C. & Poulogiannis, G., 16 Mar 2017, In: Molecular Cell. 65, 6, p. 999-1013.e7Research output: Contribution to journal › Article › peer-review
Open AccessFile66 Citations (Scopus)102 Downloads (Pure) -
Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis
Riessland, M., Kaczmarek, A., Schneider, S., Swoboda, K. J., Löhr, H., Bradler, C., Grysko, V., Dimitriadi, M., Hosseinibarkooie, S., Torres-Benito, L., Peters, M., Upadhyay, A., Biglari, N., Kröber, S., Hölker, I., Garbes, L., Gilissen, C., Hoischen, A., Nürnberg, G., Nürnberg, P., & 8 others, 2 Feb 2017, In: American Journal of Human Genetics. 100, 2, p. 297-315 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile89 Citations (Scopus)63 Downloads (Pure) -
2016
Decreased function of survival motor neuron protein impairs endocytic pathways
Dimitriadi, M., Derdowski, A., Kalloo, G., Maginnis, M. S., O'Hern, P., Bliska, B., Sorkaç, A., Nguyen, K. C. Q., Cook, S. J., Poulogiannis, G., Atwood, W. J., Hall, D. H. & Hart, A. C., 26 Jul 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 30, p. E4377-E4386 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)88 Downloads (Pure) -
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
Tape, C. J., Ling, S., Dimitriadi, M., McMahon, K. M., Worboys, J. D., Leong, H. S., Norrie, I. C., Miller, C. J., Poulogiannis, G., Lauffenburger, D. A. & Jørgensen, C., 5 May 2016, In: Cell. 165, 4, p. 910-920 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile151 Citations (Scopus)177 Downloads (Pure) -
C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins
Anderson, E. N., Corkins, M. E., Li, J. C., Singh, K., Parsons, S., Tucey, T. M., Sorkaç, A., Huang, H., Dimitriadi, M., Sinclair, D. A. & Hart, A. C., 1 Mar 2016, In: Mechanisms of Ageing and Development. 154, p. 30-42 13 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
2013
The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein
Kwon, D. Y., Dimitriadi, M., Terzic, B., Cable, C., Hart, A. C., Chitnis, A., Fischbeck, K. H. & Burnett, B. G., 15 Jun 2013, In: Molecular Biology of the Cell. 24, 12, p. 1863-1871 9 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
The neuroprotective drug riluzole acts via small conductance Ca2+ -activated K+ supchannels to ameliorate defects in spinal muscular atrophy models
Dimitriadi, M., Kye, M. J., Kalloo, G., Yersak, J. M., Sahin, M. & Hart, A. C., 10 Apr 2013, In: Journal of Neuroscience. 33, 15, p. 6557-6562 6 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
2010
Conserved genes act as modifiers of invertebrate SMN loss of function defects.
Dimitriadi, M., Sleigh, J. N., Walker, A., Chang, H. C., Sen, A., Kalloo, G., Harris, J., Barsby, T., Walsh, M. B., Satterlee, J. S., Li, C., Van Vactor, D., Artavanis-Tsakonas, S. & Hart, A. C., 28 Oct 2010, In: PLoS Genetics. 6, 10, e1001172.Research output: Contribution to journal › Article › peer-review
Open AccessFile79 Citations (Scopus)37 Downloads (Pure) -
Neurodegenerative disorders: Insights from the nematode Caenorhabditis elegans
Dimitriadi, M. & Hart, A. C., Oct 2010, In: Neurobiology of Disease. 40, 1, p. 4-11 8 p.Research output: Contribution to journal › Article › peer-review
60 Citations (Scopus) -
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
Poulogiannis, G., McIntyre, R. E., Dimitriadi, M., Apps, J. R., Wilson, C. H., Ichimura, K., Luo, F., Cantley, L. C., Wyllie, A. H., Adams, D. J. & Arends, M. J., 24 Aug 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 34, p. 15145-15150 6 p.Research output: Contribution to journal › Article › peer-review
161 Citations (Scopus) -
2008
p53-independent mechanisms regulate the P2-MDM2 promoter in adult astrocytic tumours
Dimitriadi, M., Poulogiannis, G., Liu, L., Bäcklund, L. M., Pearson, D. M., Ichimura, K. & Collins, V. P., 7 Oct 2008, In: British Journal of Cancer (BJC). 99, 7, p. 1144-1152 9 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
2007
Survival of cultured allogeneic limbal epithelial cells following corneal repair
Sharpe, J. R., Daya, S. M., Dimitriadi, M., Martin, R. & James, S. E., Jan 2007, In: Tissue Engineering. 13, 1, p. 123-132 10 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus)