Projects per year
Personal profile
Research interests
Mehrnoosh Ostovar obtained her PhD in organic chemistry from UCL (2005-09), where she worked in the area of natural product synthesis under the supervision of Prof. Karl Hale and Prof. Charles Marson. Upon completion of her studies, she joined Prof. Varinder Aggarwal’s group as a postdoctoral research associate in the School of Chemistry at University of Bristol. In this period, she worked on asymmetric aziridinations and also palladium-mediated annulation of vinyl aziridines with Michael acceptors to synthesize stereocontrolled substituted pyrrolidines and the application to a formal synthesis of (–)-α-Kainic Acid (2009-2012). In 2012, Mehrnoosh started working as a postdoctoral research officer for Prof. Stephen Husbands in the Department of Pharmacy and Pharmacology at University of Bath. Her research focus was on discovery and development of new opioid ligands as relapse prevention agents for the treatment of opioid abuse and as analgesics with low abuse potential. Mehrnoosh joined University of Hertfordshire in 2018. She is currently a senior lecturer in Pharmaceutical and Medicinal Chemistry with research interest in the area of medicinal chemistry.
Education/Academic qualification
Organic Chemistry , PhD, University College London (UCL)
Fellow of Higher Education Academy (FHEA), University of Hertfordshire
Member of Royal Society of Chemistry (MRSC)
External positions
Course Coordinator and Lecturer in Organic Chemistry Laboratories , New York University in London
1 Feb 2016 → …
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Design and Synthesis of Highly Potent and Selective GRK2 Inhibitors
Ostovar, M., Kirton, S. & Husbands, S.
1/05/23 → 29/02/28
Project: Research
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Evaluating academic answers generated using ChatGPT
Fergus, S., Botha, M. & Ostovar, M., 11 Apr 2023, In: Journal of Chemical Education. 100, 4, p. 1672-1675 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile100 Downloads (Pure) -
Bicyclic 6-6 Systems: Pteridines
Rossiter, S. & Ostovar, M., 2022, Comprehensive Heterocyclic Chemistry IV. Elsevier, Vol. 10. p. 796-855Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open AccessFile69 Downloads (Pure) -
The Buprenorphine Analogue BU10119 Attenuates Drug-Primed and Stress-Induced Cocaine Reinstatement in Mice
Hillhouse, T. M., Olson, K. M., Hallahan, J. E., Rysztak, L. G., Sears, B. F., Meurice, C., Ostovar, M., Koppenhaver, P. O., West, J. L., Jutkiewicz, E. M., Husbands, S. M. & Traynor, J. R., Sept 2021, In: Journal of Pharmacology and Experimental Therapeutics. 378, 3, p. 287-299 13 p.Research output: Contribution to journal › Article › peer-review
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Discovery of novel small molecule inhibitors of S100P, with in vitro anti-metastatic effects on pancreatic cancer cells
Camara, R., Ogbeni, D., Gerstmann, L., Ostovar, M., Hurer, E., Scott, M., Mahmoud, N., Radon, T., Crnogorac-Jurcevic, T., Patel, P., Mackenzie, L. S., Chau, D., Kirton, S. & Rossiter, S., 1 Oct 2020, In: European Journal of Medicinal Chemistry. 203, 112621.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)70 Downloads (Pure) -
Antidepressant-like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice
Almatroudi, A., Ostovar, M., Bailey, C. P., Husbands, S. M. & Bailey, S. J., Jul 2018, In: British Journal of Pharmacology. 175, 14, p. 2869-2880 12 p.Research output: Contribution to journal › Article › peer-review