Projects per year
Personal profile
Overview
Dr. Shoib Siddiqui is a reader in cancer immunotherapy in the School of Health, Medicine and Life Sciences at the University of Hertfordshire, UK. Before starting his position at UH, he was working as an Assistant Professor at the American University of Ras Al Khaimah (AURAK), UAE.
He worked as a postdoctoral researcher in the lab of Prof. Ajit Varki at University of California, San Diego (UCSD), California, USA from 2014 through 2018. His research work focused on the role of sialic acids and Siglecs (Sialic acid binding lectins) in cancer, Alzheimer’s, and sepsis. Dr. Shoib has extensively studied cancer in his Ph.D. and postdoctoral research. He did his Ph.D. dissertation at ETH Zurich, Switzerland in the lab of Prof. Michael Detmar. For his Ph.D dissertation, he investigated the role of neuropilin-2 (Nrp2), a cell surface receptor, in skin inflammation and cancer progression. Dr. Shoib obtained his Master of Sciences (M.Sc.) in Biotechnology from the Indian Institute of Technology-Bombay of Powai, Mumbai, India in 2008. His field of interest is cancer biology, immunology and glycobiology. In his research career, Dr. Shoib has published ground-breaking work in the most reputable journals such as Journal of Clinical Investigation (JCI), PNAS, Blood, Circulation Research, EMBO and, JBC. He would like to further focus his research on finding the biomarker and studying the novel pathways associated with cancer progression.
Education/Academic qualification
Vascular Biology, Immunology and cancer biology, Ph.D., Role of neuropilin-2 in skin inflammation and lymphatic function, ETH-Zurich
18 Aug 2009 → 11 Sept 2011
Award Date: 11 Sept 2013
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Collaborations and top research areas from the last five years
Projects
- 4 Finished
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Investigating compounds to treat Colorectal cancer by targeting Siglec-15
Patel, H. (PI) & Siddiqui, S. (CoI)
Institute of Biomedical Science
1/09/24 → 30/04/25
Project: Research
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project Feasibility of Targeting Intimal Hyperplasia and Vascular Calcification for the treatment of Coronary Artery Disease via the Inhibition of ADAMTS-7 with Precision-Directed Catalytic Cleft-Binding Antibodies.
Rahman, S. (PI) & Siddiqui, S. (CoI)
1/06/22 → 31/12/22
Project: Research
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Developing first-in-class RNAi therapeutics for hard-to-treat cancers
Siddiqui, S. (PI)
1/03/22 → 30/08/22
Project: Research
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UK-China Alliance: Development of the virtual centre of academic excellence for mycotoxin reduction, enhanced nutrition and food safety.
Medina, A. (PI), Verheecke-Vaessen, C. (CoPI), Garcia-Cela, E. (PI), Siddiqui, S. (Researcher) & Vafeiadou, K. (Researcher)
1/01/22 → 31/12/23
Project: Research
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'NEW CHALCONE COMPOUND EXHIBITS MICRORNA-MEDIATED ANTICANCER PROPERTIES IN GLIOBLASTOMA'
Mustafov, D., Siddiqui, S., Ahmad, I., Waseem, S., Gkantalis, J., Charlton, J., Garcia, P. & Braoudaki, M., 26 Sept 2025, In: PLoS ONE. 23 p., 0330624.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)35 Downloads (Pure) -
Innate extracellular mouse Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors
Borges, T. J., Lima, K., Murshid, A., Lape, I. T., Rigo, M. M., Lang, B. J., Teani, T. J., Siddiqui, S. S., Riella, L. V., Bonorino, C. & Calderwood, S. K., 30 Jul 2025, In: Cell Stress and Chaperones. 30, 4, p. 1-16 16 p., 100083.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)16 Downloads (Pure) -
New microRNA-based therapies reveal common targets in paediatric medulloblastoma and adult glioblastoma
Mustafov, D., Thomas, L., Siddiqui, S., George Lambrou, I. & Braoudaki, M., 2 Jul 2025, In: Scientific Reports. 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)29 Downloads (Pure) -
Revolutionising IBD Research: Investigating compounds to treat Colorectal Cancer
Patel, H. & Siddiqui, S., 18 Nov 2024, THE BIOMEDICAL SCIENTIST, p. 26-27.Research output: Contribution to specialist publication › Article
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Differential expression of ST6GALNAC1 and ST6GALNAC2 and their clinical relevance to colorectal cancer progression
Ahmad, M. S., Braoudaki, M. & Siddiqui, S., 30 Sept 2024, In: PLoS ONE. 19, 9, p. 1-24 24 p., e0311212.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)20 Downloads (Pure)