Personal profile

Research interests

My main research interest is in the area of Clostridium difficile infection and specifically the study of this pathogenic organism in vitro with regard to its pathogenesis.  The research areas I have experience in with this pathogen include:

  • Susceptibility testing and resistance development evaluations for novel antimicrobial agents
  • In vitro assays to assess antimicrobial activity of antibiotics and disinfectants against spores
  • Evaluation of novel therapeutics and their effect on the microbial ecology of the gut and C. difficile using complex in vitro models of the human colon
  • Studies of C. difficile epidemiology (human and animal/veterinary) in the United Kingdom

I also have experience of working with other pathogenic bacteria in vitro such as methicillin-resistant Staphylococcus aureus and multi-drug resistant Gram-negative bacteria.  My research with these organisms has centred around:

  • determining antimicrobial activity (MIC, MBC, kill curves)
  • bacteriophage isolation, purification and efficacy testing
  • biofilm studies

Teaching specialisms


PhD Medical Microbiology (2002-2006) -  University of Leeds

BSc (Hons) Biomedical Sciences (class 1) (1998-2002) University of West of England



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