Effect of social housing on development of STZ induced pain, in rats, assessed using VFH (evoked) and naturalistic (non-evoked) burrowing end-points:

Project: Research

Project Details

Key findings

The streptozocin model of diabetes induces neuropathic pain, impaired burrowing and transient anhedonia in rats
The impaired sucrose preference and burrowing observed in the early stages of STZ induced diabetes are objective paradigms that may reflect spontaneous pain.

Key data has been published as posters at the BPS, AISP (Pain Congress, Japan), NC3Rs conferences and is under review to be published as a full paper in Behavioural pharmacology
Effective start/end date26/06/1517/07/15


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