Smart polymers to replace antibodies in diagnostic testing

  • Cook, Michael T. (PI)

Project: Other

Project Details


The aim of the proposed project is to evaluate smart “thermoresponsive” polymers to recognize antigens as an alternative to animal-derived antibodies.

The objectives are:
1) Synthesise a library of temperature-responsive copolymers with the potential to recognize an HIV fragment (weeks 1-3)
2) Synthesise a peptide sequence associated with the viral attachment ligand of HIV (RIKQIINMWQKVGK) (weeks 3-6)
3) Evaluate the ability of the temperature-responsive copolymers to recognize HIV and respond by a change in physical state (weeks 6-8)
Effective start/end date14/06/199/08/19


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