Synthesis of 4-(3-methyl-but-1-enyl)-3,5,3’,4’-tetrahydroxystilbene (arachidin-1) and resveratrol analogues including click chemistry strategies

Project: Other

Project Details


Resveratrol is one of a number of plant defence compounds produced in grapes and other plants, which is of interest because of its anti-inflammatory and cardioprotective properties. Many natural resveratrol analogues and synthetic analogues have also shown anticancer properties. The analogue arachidin-1, produced by peanuts, has been shown to have superior activity in preventing the expression of the inflammatory COX-2 enzyme. This project aims to develop a high-yielding synthesis of arachidin-1, as well as investigating novel synthetic analogues, which will be tested for their anti-inflammatory and anticancer properties.
Effective start/end date1/02/101/02/15


Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.