244 Recurrence pattern post surgical resection of lung cancer with curative intent

Introduction
Surgery in early-stage NSCLC offers the highest chances of long-term survival. However, recurrence is a real concern (1).
Method
252 patients who had been diagnosed with non-small cell lung carcinoma at the ENH NHS Trust and had undergone curative intent surgery between 2010 and 2019, were reviewed for rates of post surgical recurrence...
Results
62 patients, (24.6%) experienced cancer recurrence following their surgical treatment. 33 patients (13.1%) were observed to have recurrences at local sites, while 29 patients, (11.51%) developed distant metastases. The range of recurrence following surgery extends from a minimum of 55 days to a maximum of 3583 days, with a mean 868.69 days ±763.81 days. Figure 1 shows the density curve of days to recurrence, which is positively skewed to the right with a peak around 500–600 days, indicating...
Conclusion
The risk of recurrence is typically highest soon after surgery and then decreases over time. There exists significant heterogeneity in this timeframe among different individuals. Follow up periods following surgery should consider the non-negligible probability of late recurrence...