TY - CHAP
T1 - 3D Printing: Advancements in the Development of Personalised Pharmaceuticals for Older Adults
AU - Awad, Atheer
AU - Januskaite, Patricija
AU - Alkahtani, Manal
AU - Orlu, Mine
AU - Basit, Abdul W.
N1 - © 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1007/978-3-031-35811-1_7
PY - 2023/11/11
Y1 - 2023/11/11
N2 - Three-dimensional (3D) printing is a revolutionary additive manufacturing technology that constructs objects layer-by-layer. This versatile technology encompasses various processes and possesses unique properties. While originally not intended for this purpose, 3D printing has emerged as a promising approach for personalised pharmaceutical production, specifically Printlets™, which are customised dosage forms. The ageing population presents enduring challenges, and 3D printing offers innovative solutions tailored to this patient subgroup. These solutions encompass a wide range of dosage forms, including multi-drug formulations, orally disintegrating tablets, chewable medicines, multiparticulate systems, and formulations for visually or physically impaired patients. Moreover, besides solid oral dosage forms, 3D printing can also fabricate patient-specific devices for drug delivery via the auricular, topical, intravesical, or vaginal routes. This chapter provides an overview of different 3D printing technologies, highlights the various dosage forms suitable for older patients, and briefly discusses the integration of 3D printing with other advanced digital health technologies.
AB - Three-dimensional (3D) printing is a revolutionary additive manufacturing technology that constructs objects layer-by-layer. This versatile technology encompasses various processes and possesses unique properties. While originally not intended for this purpose, 3D printing has emerged as a promising approach for personalised pharmaceutical production, specifically Printlets™, which are customised dosage forms. The ageing population presents enduring challenges, and 3D printing offers innovative solutions tailored to this patient subgroup. These solutions encompass a wide range of dosage forms, including multi-drug formulations, orally disintegrating tablets, chewable medicines, multiparticulate systems, and formulations for visually or physically impaired patients. Moreover, besides solid oral dosage forms, 3D printing can also fabricate patient-specific devices for drug delivery via the auricular, topical, intravesical, or vaginal routes. This chapter provides an overview of different 3D printing technologies, highlights the various dosage forms suitable for older patients, and briefly discusses the integration of 3D printing with other advanced digital health technologies.
KW - Three dimensional printing
KW - Personalized medicines
KW - Digitised healthcare and industry 4.0
KW - Rapid prototyping
KW - 3D-printed drug products
KW - Oral drug delivery systems
KW - Digitised healthcare and industry 4.0
UR - http://www.scopus.com/inward/record.url?scp=85178097060&partnerID=8YFLogxK
U2 - 10.1007/978-3-031-35811-1_7
DO - 10.1007/978-3-031-35811-1_7
M3 - Chapter
SN - 978-3-031-35810-4
T3 - AAPS Advances in the Pharmaceutical Sciences Series
SP - 157
EP - 189
BT - Pharmaceutical Formulations for Older Patients
A2 - Orlu, Mine
A2 - Liu, Fang
PB - Springer Nature Link
ER -