5,6-Methylenedioxy-2-aminoindane: from laboratory curiosity to 'legal high'

C. T. Gallagher; S. Assi; J. L. Stair; S. Fergus; Ornella Corazza; John Corkery; Fabrizio Schifano

doi:10.1002/hup.1255

5,6-Methylenedioxy-2-aminoindane: from laboratory curiosity to 'legal high'

C. T. Gallagher, S. Assi, J. L. Stair, S. Fergus, Ornella Corazza, John Corkery, Fabrizio Schifano

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

The fully synthetic 'legal high' 5,6-methylenedioxy-2-aminoindane (MDAI) is an analogue of 3,4-methylenedioxymethamphetamine. Although developed in the 1990s, it was not widely abused until 2010. However, mephedrone was banned in the UK in April 2010, and almost immediately, MDAI was widely advertised as a legal alternative. This paper provides both an overview of the current state of knowledge of MDAI and a critical analysis of online available information relating to its psychoactive effects, adverse reactions and use in combination with other drugs.

Original language	English
Pages (from-to)	106-112
Number of pages	7
Journal	Human Psychopharmacology: Clinical and Experimental
Volume	27
Issue number	2
DOIs	https://doi.org/10.1002/hup.1255
Publication status	Published - 1 Mar 2012

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abstract = "The fully synthetic 'legal high' 5,6-methylenedioxy-2-aminoindane (MDAI) is an analogue of 3,4-methylenedioxymethamphetamine. Although developed in the 1990s, it was not widely abused until 2010. However, mephedrone was banned in the UK in April 2010, and almost immediately, MDAI was widely advertised as a legal alternative. This paper provides both an overview of the current state of knowledge of MDAI and a critical analysis of online available information relating to its psychoactive effects, adverse reactions and use in combination with other drugs.",

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AB - The fully synthetic 'legal high' 5,6-methylenedioxy-2-aminoindane (MDAI) is an analogue of 3,4-methylenedioxymethamphetamine. Although developed in the 1990s, it was not widely abused until 2010. However, mephedrone was banned in the UK in April 2010, and almost immediately, MDAI was widely advertised as a legal alternative. This paper provides both an overview of the current state of knowledge of MDAI and a critical analysis of online available information relating to its psychoactive effects, adverse reactions and use in combination with other drugs.

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5,6-Methylenedioxy-2-aminoindane: from laboratory curiosity to 'legal high'

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