A comparison of methods to determine neuronal phase-response curves

Ben Torben-Nielsen, Marylka Uusisaari, Klaus M. Stiefel

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    17 Citations (Scopus)
    32 Downloads (Pure)


    The phase-response curve (PRC) is an important tool to determine the excitability type of single neurons which reveals consequences for their synchronizing properties. We review five methods to compute the PRC from both model data and experimental data and compare the numerically obtained results from each method. The main difference between the methods lies in the reliability which is influenced by the fluctuations in the spiking data and the number of spikes available for analysis. We discuss the significance of our results and provide guidelines to choose the best method based on the available data

    Original languageEnglish
    Article number6
    Number of pages11
    JournalFrontiers in Neuroinformatics
    Publication statusPublished - 2010


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