A review of adherence to drug therapy in patients with overactive bladder

R.K. Basra; A. Wagg; C. Chapple; L. Cardozo; D. Castro-Diaz; M.E. Pons; M. Kirby; I. Milsom; M. Vierhout; P. van Kerrebroeck; C. Kelleher

doi:10.1111/j.1464-410X.2008.07769.x

A review of adherence to drug therapy in patients with overactive bladder

R.K. Basra, A. Wagg, C. Chapple, L. Cardozo, D. Castro-Diaz, M.E. Pons, M. Kirby, I. Milsom, M. Vierhout, P. van Kerrebroeck, C. Kelleher

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123 Citations (Scopus)

Abstract

Drug therapy for overactive bladder (OAB) is associated with improvements in symptoms and quality of life, but the short- and long-term adherence and persistence is suboptimal. In this review we outline methods of measuring, and factors affecting, adherence to pharmacotherapy in patients with OAB. Clinical practice suggests that adherence rates reported in clinical trials are much greater than in real practice. Factors affecting adherence include psychological and social variables that might alter patients’ perception of the benefits of taking medication, and the effect of comorbidity and polypharmacy. Whilst there is some evidence that lack of efficacy and side-effects are contributory, these additional factors are also important.

Original language	English
Pages (from-to)	774-779
Journal	BJU International
Volume	102
Issue number	7
DOIs	https://doi.org/10.1111/j.1464-410X.2008.07769.x
Publication status	Published - 2008

Keywords

adherence
overactive bladder
pharmacotherapy

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10.1111/j.1464-410X.2008.07769.x

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abstract = "Drug therapy for overactive bladder (OAB) is associated with improvements in symptoms and quality of life, but the short- and long-term adherence and persistence is suboptimal. In this review we outline methods of measuring, and factors affecting, adherence to pharmacotherapy in patients with OAB. Clinical practice suggests that adherence rates reported in clinical trials are much greater than in real practice. Factors affecting adherence include psychological and social variables that might alter patients{\textquoteright} perception of the benefits of taking medication, and the effect of comorbidity and polypharmacy. Whilst there is some evidence that lack of efficacy and side-effects are contributory, these additional factors are also important.",

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T1 - A review of adherence to drug therapy in patients with overactive bladder

AU - Basra, R.K.

AU - Wagg, A.

AU - Chapple, C.

AU - Cardozo, L.

AU - Castro-Diaz, D.

AU - Pons, M.E.

AU - Kirby, M.

AU - Milsom, I.

AU - Vierhout, M.

AU - van Kerrebroeck, P.

AU - Kelleher, C.

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PY - 2008

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N2 - Drug therapy for overactive bladder (OAB) is associated with improvements in symptoms and quality of life, but the short- and long-term adherence and persistence is suboptimal. In this review we outline methods of measuring, and factors affecting, adherence to pharmacotherapy in patients with OAB. Clinical practice suggests that adherence rates reported in clinical trials are much greater than in real practice. Factors affecting adherence include psychological and social variables that might alter patients’ perception of the benefits of taking medication, and the effect of comorbidity and polypharmacy. Whilst there is some evidence that lack of efficacy and side-effects are contributory, these additional factors are also important.

AB - Drug therapy for overactive bladder (OAB) is associated with improvements in symptoms and quality of life, but the short- and long-term adherence and persistence is suboptimal. In this review we outline methods of measuring, and factors affecting, adherence to pharmacotherapy in patients with OAB. Clinical practice suggests that adherence rates reported in clinical trials are much greater than in real practice. Factors affecting adherence include psychological and social variables that might alter patients’ perception of the benefits of taking medication, and the effect of comorbidity and polypharmacy. Whilst there is some evidence that lack of efficacy and side-effects are contributory, these additional factors are also important.

KW - adherence

KW - overactive bladder

KW - pharmacotherapy

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DO - 10.1111/j.1464-410X.2008.07769.x

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A review of adherence to drug therapy in patients with overactive bladder

Abstract

Keywords

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