TY - JOUR
T1 - A Snapshot of photoresponsive liposomes in cancer chemotherapy and immunotherapy: opportunities and challenges
AU - Youness, Rana A.
AU - Hasan, Adham
AU - Efthimiadou, Eleni
AU - Mekky, Radwa
AU - Braoudaki, Maria
AU - Fahmy, Sherif Ashraf
N1 - © 2023 The Authors. Published by American Chemical Society. This is an open access article under the Creative Commons Attribution-NonCommercial-NoDerivatives CC BY-NC-ND licence, https://creativecommons.org/licenses/by-nc-nd/4.0
PY - 2023/11/28
Y1 - 2023/11/28
N2 - To provide precise medical regimens, photonics technologies have been involved in the field of nanomedicine. Phototriggered liposomes have been cast as promising nanosystems that achieve controlled release of payloads in several pathological conditions such as cancer, autoimmune, and infectious diseases. In contrast to the conventional liposomes, this photoresponsive element greatly improves therapeutic efficacy and reduces the adverse effects of gene/drug therapy during treatment. Recently, cancer immunotherpay has been one of the hot topics in the field of oncology due to the great success and therapeutic benefits that were well-recognized by the patients. However, several side effects have been encountered due to the unmonitored augmentation of the immune system. This Review highlights the most recent advancements in the development of photoresponsive liposome nanosystems in the field of oncology, with a specific emphasis on challenges and opportunities in the field of cancer immunotherapy.
AB - To provide precise medical regimens, photonics technologies have been involved in the field of nanomedicine. Phototriggered liposomes have been cast as promising nanosystems that achieve controlled release of payloads in several pathological conditions such as cancer, autoimmune, and infectious diseases. In contrast to the conventional liposomes, this photoresponsive element greatly improves therapeutic efficacy and reduces the adverse effects of gene/drug therapy during treatment. Recently, cancer immunotherpay has been one of the hot topics in the field of oncology due to the great success and therapeutic benefits that were well-recognized by the patients. However, several side effects have been encountered due to the unmonitored augmentation of the immune system. This Review highlights the most recent advancements in the development of photoresponsive liposome nanosystems in the field of oncology, with a specific emphasis on challenges and opportunities in the field of cancer immunotherapy.
UR - http://www.scopus.com/inward/record.url?scp=85179166957&partnerID=8YFLogxK
U2 - 10.1021/acsomega.3c04134
DO - 10.1021/acsomega.3c04134
M3 - Review article
C2 - 38046305
SN - 2470-1343
VL - 8
SP - 44424
EP - 44436
JO - ACS Omega
JF - ACS Omega
IS - 47
ER -