A Snapshot of photoresponsive liposomes in cancer chemotherapy and immunotherapy: opportunities and challenges

Rana A. Youness, Adham Hasan, Eleni Efthimiadou, Radwa Mekky, Maria Braoudaki, Sherif Ashraf Fahmy

Research output: Contribution to journalReview articlepeer-review

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Abstract

To provide precise medical regimens, photonics technologies have been involved in the field of nanomedicine. Phototriggered liposomes have been cast as promising nanosystems that achieve controlled release of payloads in several pathological conditions such as cancer, autoimmune, and infectious diseases. In contrast to the conventional liposomes, this photoresponsive element greatly improves therapeutic efficacy and reduces the adverse effects of gene/drug therapy during treatment. Recently, cancer immunotherpay has been one of the hot topics in the field of oncology due to the great success and therapeutic benefits that were well-recognized by the patients. However, several side effects have been encountered due to the unmonitored augmentation of the immune system. This Review highlights the most recent advancements in the development of photoresponsive liposome nanosystems in the field of oncology, with a specific emphasis on challenges and opportunities in the field of cancer immunotherapy.
Original languageEnglish
Pages (from-to)44424-44436
Number of pages13
JournalACS Omega
Volume8
Issue number47
Early online date14 Nov 2023
DOIs
Publication statusPublished - 28 Nov 2023

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