Amanicadol, a pimarane-type diterpene from Phlomis amanica Vierch

F.N. Yalçin, T. Ersöz, I. Çaliş, E. Bedir, A.A. Dönmez, M. Stavri, S. Gibbons, Mire Zloh

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Fractionation of the methanol extract of Phlomis amanica resulted in the isolation of a new pimarane type diterpene, amanicadol (1), together with the known glycosides lamiide, verbascoside (= acteoside), syringaresinol-4-O-β- glucoside, liriodendrin, syringin, and a caffeic acid ester, chlorogenic acid. The structure of the new compound was established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Molecular modeling studies on 1 were conducted and showed that it exhibited low conformational flexibility. Additionally, NMR chemical shifts were calculated for 1 in vacuo, and calculated values were in very close agreement with those found experimentally.
Original languageEnglish
Pages (from-to)1433-1436
Number of pages4
JournalZeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Issue number11
Publication statusPublished - 1 Nov 2006


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