TY - JOUR
T1 - Amanicadol, a pimarane-type diterpene from Phlomis amanica Vierch
AU - Yalçin, F.N.
AU - Ersöz, T.
AU - Çaliş, I.
AU - Bedir, E.
AU - Dönmez, A.A.
AU - Stavri, M.
AU - Gibbons, S.
AU - Zloh, Mire
PY - 2006/11/1
Y1 - 2006/11/1
N2 - Fractionation of the methanol extract of Phlomis amanica resulted in the isolation of a new pimarane type diterpene, amanicadol (1), together with the known glycosides lamiide, verbascoside (= acteoside), syringaresinol-4-O-β- glucoside, liriodendrin, syringin, and a caffeic acid ester, chlorogenic acid. The structure of the new compound was established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Molecular modeling studies on 1 were conducted and showed that it exhibited low conformational flexibility. Additionally, NMR chemical shifts were calculated for 1 in vacuo, and calculated values were in very close agreement with those found experimentally.
AB - Fractionation of the methanol extract of Phlomis amanica resulted in the isolation of a new pimarane type diterpene, amanicadol (1), together with the known glycosides lamiide, verbascoside (= acteoside), syringaresinol-4-O-β- glucoside, liriodendrin, syringin, and a caffeic acid ester, chlorogenic acid. The structure of the new compound was established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Molecular modeling studies on 1 were conducted and showed that it exhibited low conformational flexibility. Additionally, NMR chemical shifts were calculated for 1 in vacuo, and calculated values were in very close agreement with those found experimentally.
UR - http://www.scopus.com/inward/record.url?scp=33845699222&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:33845699222
SN - 0932-0776
VL - 61
SP - 1433
EP - 1436
JO - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
JF - Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
IS - 11
ER -