Anti-BiP antibody levels in juvenile idiopathic arthritis (JIA)

M.D. Bodman-Smith, M.F. Fife, H. Wythe, V.M. Corrigal, G.S. Panayi, L.R. Wedderburn, P. Woo

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    8 Citations (Scopus)

    Abstract

    We have previously described the human heat shock protein BiP (immunoglobulin binding protein; glucose regulated protein 78) as an autoantigen in rheumatoid arthritis [1]. Antibodies to BiP have been described in the serum of RA patients by ourselves and other groups [2, 3] and we have recently described anti-BiP antibodies in the synovial fluid of RA patients and the serum of patients with primary Sjögren's syndrome [3]. Moreover anti-BiP antibodies have been shown to be elevated in animal models of arthritis [1].
    Original languageEnglish
    Pages (from-to)1305-1306
    JournalRheumatology
    Volume43
    Issue number10
    DOIs
    Publication statusPublished - 2004

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