Aryl sulfones: A new class of γ-secretase inhibitors

M. Teall; P. Oakley; T. Harrison; D. Shaw; E. Kay; J. Elliott; U. Gerhard; J.L. Castro; M. Shearman; R.G. Ball; N.N. Tsou

doi:10.1016/j.bmcl.2004.12.017

Aryl sulfones: A new class of γ-secretase inhibitors

M. Teall, P. Oakley, T. Harrison, D. Shaw, E. Kay, J. Elliott, U. Gerhard, J.L. Castro, M. Shearman, R.G. Ball, N.N. Tsou

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors for the potential treatment of Alzheimer's disease is described

Original language	English
Pages (from-to)	2685-2688
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	15
Issue number	10
DOIs	https://doi.org/10.1016/j.bmcl.2004.12.017
Publication status	Published - 16 May 2005

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title = "Aryl sulfones: A new class of γ-secretase inhibitors",

abstract = "The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors for the potential treatment of Alzheimer's disease is described",

author = "M. Teall and P. Oakley and T. Harrison and D. Shaw and E. Kay and J. Elliott and U. Gerhard and J.L. Castro and M. Shearman and R.G. Ball and N.N. Tsou",

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T2 - A new class of γ-secretase inhibitors

AU - Teall, M.

AU - Oakley, P.

AU - Harrison, T.

AU - Shaw, D.

AU - Kay, E.

AU - Elliott, J.

AU - Gerhard, U.

AU - Castro, J.L.

AU - Shearman, M.

AU - Ball, R.G.

AU - Tsou, N.N.

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Y1 - 2005/5/16

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SP - 2685

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JO - Bioorganic and Medicinal Chemistry Letters

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IS - 10

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Aryl sulfones: A new class of γ-secretase inhibitors

Abstract

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