Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains: Structural insights based on similarity and molecular interaction fields

B.J. Drakulić; M. Stavri; S. Gibbons; Ž.S. Žižak; T.Ž. Verbić; I.O. Juranić; Mire Zloh

doi:10.1002/cmdc.200900273

Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains: Structural insights based on similarity and molecular interaction fields

B.J. Drakulić
, M. Stavri
, S. Gibbons
, Ž.S. Žižak
, T.Ž. Verbić
, I.O. Juranić
, Mire Zloh

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

(Chemical Equation Presented) Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction fields and similarity studies between investigated molecules and fluoroquinolone antibiotics.

Original language	English
Pages (from-to)	1971-1975
Number of pages	5
Journal	ChemMedChem
Volume	4
Issue number	12
DOIs	https://doi.org/10.1002/cmdc.200900273
Publication status	Published - 7 Dec 2009

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abstract = "(Chemical Equation Presented) Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction fields and similarity studies between investigated molecules and fluoroquinolone antibiotics.",

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T2 - Structural insights based on similarity and molecular interaction fields

AU - Drakulić, B.J.

AU - Stavri, M.

AU - Gibbons, S.

AU - Žižak, Ž.S.

AU - Verbić, T.Ž.

AU - Juranić, I.O.

AU - Zloh, Mire

PY - 2009/12/7

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AB - (Chemical Equation Presented) Similar structure=similar activity? The effect of substituents on the antibacterial activity of aryldiketo acids has been rationalised by molecular interaction fields and similarity studies between investigated molecules and fluoroquinolone antibiotics.

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Aryldiketo acids have antibacterial activity against MDR Staphylococcus aureus strains: Structural insights based on similarity and molecular interaction fields

Abstract

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