Bacterial endotoxin rapidly stimulates prolonged endothelium-dependent vasodilatation in the isolated perfused rat heart

A. R. Baydoun, R. D. Foale, G.E. Mann

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    34 Citations (Scopus)
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    Abstract

    The effects of bacterial lipopolysaccharide (Escherichia coli 0111-B4; LPS) on coronary vascular tone were examined in the isolated perfused rat heart. The role of nitric oxide and/or prostaglandin products of the cyclooxygenase pathway in mediating the actions of LPS were also investigated.
    Original languageEnglish
    Pages (from-to)987-991
    JournalBritish Journal of Pharmacology
    Volume109
    Publication statusPublished - 1993

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