Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Daniel F. McWilliams; Patrick D. W. Kiely; Adam Young; David A. Walsh

doi:10.1186/1471-2474-14-153

Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Daniel F. McWilliams, Patrick D. W. Kiely, Adam Young, David A. Walsh

School of Life and Medical Sciences

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

39 Downloads (Pure)

Abstract

Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.

Original language	English
Article number	153
Number of pages	7
Journal	BMC Musculoskeletal Disorders
Volume	14
DOIs	https://doi.org/10.1186/1471-2474-14-153
Publication status	Published - May 2013

Keywords

Adult
Aged
Antirheumatic Agents
Arthritis, Rheumatoid
Cohort Studies
Disability Evaluation
Drug Substitution
Drug Therapy, Combination
Drug-Related Side Effects and Adverse Reactions
Female
Health Status
Humans
Hydroxychloroquine
Logistic Models
Male
Methotrexate
Middle Aged
Sulfasalazine
Treatment Failure
Treatment Outcome

Access to Document

10.1186/1471-2474-14-153

906781
© 2013 McWilliams et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Final published version, 320 KB

Cite this

@article{cbcc88fc6bb2493d97a1a31a40c12dd6,

title = "Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort",

abstract = "Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.",

keywords = "Adult, Aged, Antirheumatic Agents, Arthritis, Rheumatoid, Cohort Studies, Disability Evaluation, Drug Substitution, Drug Therapy, Combination, Drug-Related Side Effects and Adverse Reactions, Female, Health Status, Humans, Hydroxychloroquine, Logistic Models, Male, Methotrexate, Middle Aged, Sulfasalazine, Treatment Failure, Treatment Outcome",

author = "McWilliams, {Daniel F.} and Kiely, {Patrick D. W.} and Adam Young and Walsh, {David A.}",

note = "{\textcopyright} 2013 McWilliams et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited",

year = "2013",

month = may,

doi = "10.1186/1471-2474-14-153",

language = "English",

volume = "14",

journal = "BMC Musculoskeletal Disorders",

issn = "1471-2474",

publisher = "BioMed Central (BMC)",

}

TY - JOUR

T1 - Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis

T2 - experience in the ERAN inception cohort

AU - McWilliams, Daniel F.

AU - Kiely, Patrick D. W.

AU - Young, Adam

AU - Walsh, David A.

N1 - © 2013 McWilliams et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

PY - 2013/5

Y1 - 2013/5

N2 - Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.

AB - Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.

KW - Adult

KW - Aged

KW - Antirheumatic Agents

KW - Arthritis, Rheumatoid

KW - Cohort Studies

KW - Disability Evaluation

KW - Drug Substitution

KW - Drug Therapy, Combination

KW - Drug-Related Side Effects and Adverse Reactions

KW - Female

KW - Health Status

KW - Humans

KW - Hydroxychloroquine

KW - Logistic Models

KW - Male

KW - Methotrexate

KW - Middle Aged

KW - Sulfasalazine

KW - Treatment Failure

KW - Treatment Outcome

U2 - 10.1186/1471-2474-14-153

DO - 10.1186/1471-2474-14-153

M3 - Article

C2 - 23634781

SN - 1471-2474

VL - 14

JO - BMC Musculoskeletal Disorders

JF - BMC Musculoskeletal Disorders

M1 - 153

ER -

Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Abstract

Keywords

Access to Document

Fingerprint

Cite this