Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Daniel F. McWilliams, Patrick D. W. Kiely, Adam Young, David A. Walsh

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Abstract

Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.
Original languageEnglish
Article number153
Number of pages7
JournalBMC Musculoskeletal Disorders
Volume14
DOIs
Publication statusPublished - May 2013

Keywords

  • Adult
  • Aged
  • Antirheumatic Agents
  • Arthritis, Rheumatoid
  • Cohort Studies
  • Disability Evaluation
  • Drug Substitution
  • Drug Therapy, Combination
  • Drug-Related Side Effects and Adverse Reactions
  • Female
  • Health Status
  • Humans
  • Hydroxychloroquine
  • Logistic Models
  • Male
  • Methotrexate
  • Middle Aged
  • Sulfasalazine
  • Treatment Failure
  • Treatment Outcome

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