Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Daniel F. McWilliams; Patrick D. W. Kiely; Adam Young; David A. Walsh

doi:10.1186/1471-2474-14-153

Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Daniel F. McWilliams
, Patrick D. W. Kiely
, Adam Young
, David A. Walsh

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

44 Downloads (Pure)

Abstract

Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.

Original language	English
Article number	153
Number of pages	7
Journal	BMC Musculoskeletal Disorders
Volume	14
DOIs	https://doi.org/10.1186/1471-2474-14-153
Publication status	Published - May 2013

Keywords

Adult
Aged
Antirheumatic Agents
Arthritis, Rheumatoid
Cohort Studies
Disability Evaluation
Drug Substitution
Drug Therapy, Combination
Drug-Related Side Effects and Adverse Reactions
Female
Health Status
Humans
Hydroxychloroquine
Logistic Models
Male
Methotrexate
Middle Aged
Sulfasalazine
Treatment Failure
Treatment Outcome

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10.1186/1471-2474-14-153

906781
© 2013 McWilliams et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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title = "Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort",

abstract = "Outcomes in early Rheumatoid Arthritis (RA) may be improved by rapidly establishing a stable and effective disease modifying anti-rheumatic drug (DMARD) treatment regimen. We aimed to investigate whether baseline factors and initial treatment strategies are associated with changes to the first DMARD treatment, due to either Lack of Efficacy (LoE) or Adverse Drug Reaction (ADR) within 2 years of presentation.",

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author = "McWilliams, \{Daniel F.\} and Kiely, \{Patrick D. W.\} and Adam Young and Walsh, \{David A.\}",

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year = "2013",

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doi = "10.1186/1471-2474-14-153",

language = "English",

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journal = "BMC Musculoskeletal Disorders",

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AU - McWilliams, Daniel F.

AU - Kiely, Patrick D. W.

AU - Young, Adam

AU - Walsh, David A.

N1 - © 2013 McWilliams et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

PY - 2013/5

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KW - Drug-Related Side Effects and Adverse Reactions

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KW - Health Status

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M1 - 153

ER -

Baseline factors predicting change from the initial DMARD treatment during the first 2 years of rheumatoid arthritis: experience in the ERAN inception cohort

Abstract

Keywords

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