Biological evaluations of novel 2,3,3-Trisphosphonate in osteoclastic and osteoblastic activities

Biochemistry, Genetics and Molecular Biology

• Bone Development 100%
• LC50 100%
• Mineralization 100%
• Docking (Molecular) 100%
• Farnesyl Pyrophosphate 100%
• Bone Regeneration 100%
• Prenylation 100%
• Anabolism 100%
• Osteoblast 100%
• Synthase 100%
• Osteolysis 100%
• Binding Affinity 100%
• Biological Activity 100%
• Cytotoxicity 100%
• Mevalonate Pathway 100%

Keyphrases

• Bisphosphonates 100%
• Biological Evaluation 100%
• Osteoblastic Activity 100%
• Osteoclastic Activity 100%
• Trisphosphonates 100%
• Osteoclastic 66%
• New Analogs 33%
• Two-phase Reaction 33%
• Computational Simulation 33%
• LC50 33%
• Osteoblast Mineralization 33%
• Molecular Docking 33%
• Bone Disease 33%
• Biological Effects 33%
• Etidronate 33%
• Mineralization Potential 33%
• Bone Regeneration 33%
• Bone Resorption 33%
• Human Farnesyl Pyrophosphate Synthase 33%
• Bone Cells 33%
• Mevalonate Pathway 33%
• Deactivation 33%
• Bone Malignancy 33%
• Binding Affinity 33%
• In Vitro Investigation 33%
• Cytotoxic Effect 33%
• Prenylation 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Bisphosphonic Acid Derivative 100%
• Mevalonic Acid 33%
• Etidronic Acid 33%
• Bone Disease 33%
• Synthetase 33%
• Farnesyl Diphosphate 33%
• Cytotoxicity 33%