Calpain activation and inhibition in organotypic rat hippocampal slice cultures deprived of oxygen and glucose

Keyphrases

• Calpain Activity 100%
• Ischemia 100%
• Hippocampal Slice Culture 100%
• Rat Hippocampal Slices 100%
• Breakdown Products 100%
• Organotypic 100%
• Calpain Inhibition 100%
• Calpain 80%
• Propidium Iodide 80%
• Neuroprotective Effect 40%
• Cell Death 40%
• Calpain Inhibitor 40%
• Post-incubation 20%
• Western Blot 20%
• High Dose 20%
• Permeant 20%
• Neuroprotective 20%
• Traumatic Brain Injury 20%
• CA1 Region 20%
• Beneficial Outcomes 20%
• Protease Inhibitors 20%
• Ischemic Cell Death 20%
• Pre-incubation 20%
• Insults 20%
• Organotypic Brain Slice Culture 20%
• Vital Dyes 20%
• Spectrin Breakdown Products 20%
• Neuronal Cell Death 20%
• Product Formation 20%
• CA3 Pyramidal Cells 20%
• Ischemic Insult 20%
• CA1 Pyramidal Cells 20%
• Leupeptin 20%
• Ischemic Damage 20%
• Toxic Effects 20%
• Incubation Period 20%
• Protease 20%

Neuroscience

• Calpain 100%
• Ischemia 62%
• Propidium Iodide 50%
• Cell Death 37%
• Neuroprotective Agent 37%
• Calpain 1 25%
• Proteinase 25%
• Neurotrauma 12%
• Leupeptin 12%
• Western Blotting 12%
• Traumatic Brain Injury 12%
• Pyramidal Cell 12%
• Neuronal Cell Death 12%
• In Vivo 12%
• Spectrin 12%