Can Kratom (Mitragyna speciosa) Alleviate COVID-19 Pain? A Case Study

Antonio Metastasio, Elisabeth Prevete, Darshan Singh, Oliver Grundmann, Walter C. Prozialeck, Charles Veltri, Giuseppe Bersani, Ornella Corazza

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)
24 Downloads (Pure)


Among the symptoms of COVID-19 fever, general malaise, pain and aches, myalgia, fatigue, and headache can affect the quality of life of patients, even after the end of the acute phase of the infection and can be long lasting. The current treatment of these symptoms, also because COVID-19 patients have been asked not to use non-steroidal anti-inflammatory drugs (NSAIDs), in particular ibuprofen are often unsatisfactory. Among the above mentioned symptoms malaise and fatigue seem the most difficult to treat. In this case report we describe the use of kratom (Mitragyna speciosa) by a patient with confirmed COVID-19 infection. What we observed was a fast and sustained relieve of the above mentioned symptoms.
Original languageEnglish
Article number594816
Number of pages6
JournalFrontiers in Psychiatry
Publication statusPublished - 19 Nov 2020


  • COVID-19
  • kratom
  • long covid
  • new psychoactive substances
  • new treatments
  • opioid
  • stimulants


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