Colorectal tumor vascularity: quantitative assessment with multidetector CT--do tumor perfusion measurements reflect angiogenesis?

Vicky Goh, Steve Halligan, Frances Daley, D. Wellsted, Thomas Guenther, Clive I Bartram

Research output: Contribution to journalArticlepeer-review

118 Citations (Scopus)

Abstract

To establish the relationships between quantitative perfusion computed tomography (CT) parameters-specifically, primary tumor blood flow, blood volume, transit time, and permeability surface-area product-and immunohistologic markers of angiogenesis in colorectal cancer.
Original languageEnglish
Pages (from-to)510-7
Number of pages8
JournalRadiology
Volume249
Issue number2
DOIs
Publication statusPublished - 2008

Keywords

  • Adenocarcinoma
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Flow Velocity
  • Colorectal Neoplasms
  • Contrast Media
  • Female
  • Glucose Transporter Type 1
  • Humans
  • Immunohistochemistry
  • Iopamidol
  • Male
  • Middle Aged
  • Neovascularization, Pathologic
  • Radiographic Image Interpretation, Computer-Assisted
  • Statistics, Nonparametric
  • Tomography, X-Ray Computed
  • Tumor Markers, Biological
  • Vascular Endothelial Growth Factor A

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