Colorectal tumor vascularity: quantitative assessment with multidetector CT--do tumor perfusion measurements reflect angiogenesis?

Vicky Goh, Steve Halligan, Frances Daley, D. Wellsted, Thomas Guenther, Clive I Bartram

    Research output: Contribution to journalArticlepeer-review

    118 Citations (Scopus)

    Abstract

    To establish the relationships between quantitative perfusion computed tomography (CT) parameters-specifically, primary tumor blood flow, blood volume, transit time, and permeability surface-area product-and immunohistologic markers of angiogenesis in colorectal cancer.
    Original languageEnglish
    Pages (from-to)510-7
    Number of pages8
    JournalRadiology
    Volume249
    Issue number2
    DOIs
    Publication statusPublished - 2008

    Keywords

    • Adenocarcinoma
    • Adult
    • Aged
    • Aged, 80 and over
    • Blood Flow Velocity
    • Colorectal Neoplasms
    • Contrast Media
    • Female
    • Glucose Transporter Type 1
    • Humans
    • Immunohistochemistry
    • Iopamidol
    • Male
    • Middle Aged
    • Neovascularization, Pathologic
    • Radiographic Image Interpretation, Computer-Assisted
    • Statistics, Nonparametric
    • Tomography, X-Ray Computed
    • Tumor Markers, Biological
    • Vascular Endothelial Growth Factor A

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