TY - JOUR
T1 - Comorbid depression in obsessive compulsive disorder (OCD)
T2 - Symptomatic differences to major depressive disorder
AU - Fineberg, Naomi
AU - Fourie, H.
AU - Gale, T.M.
AU - Sivakumaran, T.
N1 - Original article can be found at: http://www.sciencedirect.com/science/journal/01650327 Copyright Elsevier Inc. DOI: 10.1016/j.jad.2005.04.004 [Full text of this article is not available in the UHRA]
PY - 2005
Y1 - 2005
N2 - In this study, we compared the depressive symptom profile of a group of obsessive compulsive disorder (OCD) patients, with comorbid depression, to a group of patients with major depressive disorder (MDD). The two groups (n = 52 per group) were pair-wise matched on severity of depression as measured by the MÅDRS (mean 24.3 for each group) and we examined between-group differences on the individual MÅDRS item scores. The OCD group was significantly more symptomatic on items 3 (inner tension) and 9 (pessimistic thoughts) and significantly less symptomatic on items 4 (sleep) and 5 (appetite). We discuss these findings in the context of neurobiological bases for the two disorders.
AB - In this study, we compared the depressive symptom profile of a group of obsessive compulsive disorder (OCD) patients, with comorbid depression, to a group of patients with major depressive disorder (MDD). The two groups (n = 52 per group) were pair-wise matched on severity of depression as measured by the MÅDRS (mean 24.3 for each group) and we examined between-group differences on the individual MÅDRS item scores. The OCD group was significantly more symptomatic on items 3 (inner tension) and 9 (pessimistic thoughts) and significantly less symptomatic on items 4 (sleep) and 5 (appetite). We discuss these findings in the context of neurobiological bases for the two disorders.
U2 - 10.1016/j.jad.2005.04.004
DO - 10.1016/j.jad.2005.04.004
M3 - Article
SN - 0165-0327
VL - 87
SP - 327
EP - 330
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
IS - 2-3
ER -