Comparison of four methods for the determination of plasma pepsinogen concentration

I. Scott, M.J. Stear, Quintin McKellar

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Four methods for estimating plasma pepsinogen concentrations were compared to determine the most suitable for routine use. Three of the methods were colorimetric assays which used glycine-buffered albumin, albumin, or haemoglobin as their substrates. The fourth method was a radial diffusion assay which used casein in agarose as its substrate. All four methods gave reproducible results when replicates were assayed on the same day. However, the first method had the least day-to-day variation and was the only method which gave a linear relationship with different concentrations of pepsinogen in a plasma pool.
Original languageEnglish
Pages (from-to)234-7
Number of pages4
JournalResearch in Veterinary Science
Issue number3
Publication statusPublished - Nov 1995


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