Comparison of laboratory and handheld Raman instruments for the identification of counterfeit medicines

Sulaf Assi, R. Watt, T. Moffat

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Raman spectroscopy offers a rapid, simple, and nondestructive technique for the identification of counterfeit medicines. The advantages of handheld Raman spectroscopy are that it is easy to use by unskilled personnel and it can identify a test pharmaceutical product on the spot, whether the product is in solid or liquid form. However, these instruments can operate only in reflection mode, and the Raman activity of a sample is often masked by fluorescent species in the sample, especially when the analysis is made in reflection mode. The objective of this work was to compare the use of a handheld and laboratory-based Raman instruments for authentication of pharmaceutical products obtained from the world market.
    Original languageEnglish
    Pages (from-to)36-47
    JournalSpectroscopy
    Issue numberJune Supplement
    Publication statusPublished - 2011

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