Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”

G. I. Lambrou; M. Braoudaki; P. Katrakazas; I. Kouris; D. Iliopoulou; Tz Koutsouri; O. Petropoulou; D. D. Koutsouris

doi:10.1007/978-3-319-32703-7_98

Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”

G. I. Lambrou, M. Braoudaki, P. Katrakazas, I. Kouris, D. Iliopoulou, Tz Koutsouri, O. Petropoulou, D. D. Koutsouris

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Human neoplasms are considered to be diseases whose pathogenesis is attributed to genomic aberrations. Yet, it has been previously reported that genomic stability is probably not the sole “player” in tumor ontogenesis. Several genes have been identified that are considerd to be the “oncogenic drivers”. In that sense the present work manifests a hypothesis that tumor ontogenesis could be driven by genes or network of genes that get out of control or else “genes gone crazy”.

Original language	English
Title of host publication	XIV Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016
Editors	Efthyvoulos Kyriacou, Stelios Christofides, Constantinos S. Pattichis
Publisher	Springer Nature Link
Pages	507-511
Volume	57
ISBN (Print)	9783319327013
DOIs	https://doi.org/10.1007/978-3-319-32703-7_98
Publication status	E-pub ahead of print - 17 Sept 2016
Event	14th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016 - Paphos, Cyprus Duration: 31 Mar 2016 → 2 Apr 2016

Conference

Conference	14th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016
Country/Territory	Cyprus
City	Paphos
Period	31/03/16 → 2/04/16

Keywords

Complex dynamics
Gene expression
Microarray
Oscillations
Pathway
Sink

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Lambrou, G. I., Braoudaki, M., Katrakazas, P., Kouris, I., Iliopoulou, D., Koutsouri, T., Petropoulou, O., & Koutsouris, D. D. (2016). Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”. In E. Kyriacou, S. Christofides, & C. S. Pattichis (Eds.), XIV Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016 (Vol. 57, pp. 507-511). Springer Nature Link. Advance online publication. https://doi.org/10.1007/978-3-319-32703-7_98

Lambrou, G. I. ; Braoudaki, M. ; Katrakazas, P. et al. / Complex dynamics in tumor gene regulatory networks : Oncogenesis dynamics driven by “Genes Gone Crazy”. XIV Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016. editor / Efthyvoulos Kyriacou ; Stelios Christofides ; Constantinos S. Pattichis. Vol. 57 Springer Nature Link, 2016. pp. 507-511

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Lambrou, GI, Braoudaki, M, Katrakazas, P, Kouris, I, Iliopoulou, D, Koutsouri, T, Petropoulou, O & Koutsouris, DD 2016, Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”. in E Kyriacou, S Christofides & CS Pattichis (eds), XIV Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016. vol. 57, Springer Nature Link, pp. 507-511, 14th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016, Paphos, Cyprus, 31/03/16. https://doi.org/10.1007/978-3-319-32703-7_98

Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”. / Lambrou, G. I.; Braoudaki, M.; Katrakazas, P. et al.
XIV Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016. ed. / Efthyvoulos Kyriacou; Stelios Christofides; Constantinos S. Pattichis. Vol. 57 Springer Nature Link, 2016. p. 507-511.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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KW - Gene expression

KW - Microarray

KW - Oscillations

KW - Pathway

KW - Sink

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Lambrou GI, Braoudaki M, Katrakazas P, Kouris I, Iliopoulou D, Koutsouri T et al. Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”. In Kyriacou E, Christofides S, Pattichis CS, editors, XIV Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2016. Vol. 57. Springer Nature Link. 2016. p. 507-511 Epub 2016 Sept 17. doi: 10.1007/978-3-319-32703-7_98

Complex dynamics in tumor gene regulatory networks: Oncogenesis dynamics driven by “Genes Gone Crazy”

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