Confidence interval construction for proportion difference from partially validated series with two fallible classifiers

Shi-Fang Qiu, Li-Ming Wang, Man-Lai Tang, Wai-Yin Poon

Research output: Contribution to journalArticlepeer-review

Abstract

This article investigates the confidence interval (CI) construction of proportion difference for two independent partially validated series under the double-sampling scheme in which both classifiers are fallible. Several CIs based on the variance estimates recovery method of combining confidence limits from asymptotic, bootstrap, and Bayesian methods for two independent binomial proportions are developed under two models. Simulation results show that all CIs except for the bootstrap percentile-t CI and Bayesian credible interval with uniform prior under the independence model and all CIs under the dependence model generally perform well and are recommended. Two examples are used to illustrate the methodologies.

Original languageEnglish
Pages (from-to)871-896
Number of pages26
JournalJournal of Biopharmaceutical Statistics
Volume32
Issue number6
Early online date10 May 2022
DOIs
Publication statusPublished - 2 Nov 2022

Keywords

  • Humans
  • Models, Statistical
  • Bayes Theorem
  • Confidence Intervals
  • Computer Simulation

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