Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

G. Mukerji; Y. Yiangou; S. Corcoran; I. S. Selmer; G.D. Smith; C.D. Benham; C. Bountra; S. K. Agarwal; P. Anand

doi:10.1186/1471-2490-6-6

Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

G. Mukerji, Y. Yiangou, S. Corcoran, I. S. Selmer, G.D. Smith, C.D. Benham, C. Bountra, S. K. Agarwal, P. Anand

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Abstract

The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of the bladder cooling reflex. In this study, we report the distribution of the cool and menthol receptor TRPM8 in the urinary bladder in patients with overactive and painful bladder syndromes, and its relationship with clinical symptoms.

Original language	English
Article number	6
Journal	BMC Urology
Volume	6
DOIs	https://doi.org/10.1186/1471-2490-6-6
Publication status	Published - 2006

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© 2006Mukerji et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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title = "Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations",

abstract = "The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of the bladder cooling reflex. In this study, we report the distribution of the cool and menthol receptor TRPM8 in the urinary bladder in patients with overactive and painful bladder syndromes, and its relationship with clinical symptoms. ",

author = "G. Mukerji and Y. Yiangou and S. Corcoran and Selmer, {I. S.} and G.D. Smith and C.D. Benham and C. Bountra and Agarwal, {S. K.} and P. Anand",

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T1 - Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

AU - Mukerji, G.

AU - Yiangou, Y.

AU - Corcoran, S.

AU - Selmer, I. S.

AU - Smith, G.D.

AU - Benham, C.D.

AU - Bountra, C.

AU - Agarwal, S. K.

AU - Anand, P.

N1 - Original article can be found at : http://www.biomedcentral.com/bmcurol/----Copyright BioMed Central DOI : 10.1186/1471-2490-6-6

PY - 2006

Y1 - 2006

N2 - The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of the bladder cooling reflex. In this study, we report the distribution of the cool and menthol receptor TRPM8 in the urinary bladder in patients with overactive and painful bladder syndromes, and its relationship with clinical symptoms.

AB - The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of the bladder cooling reflex. In this study, we report the distribution of the cool and menthol receptor TRPM8 in the urinary bladder in patients with overactive and painful bladder syndromes, and its relationship with clinical symptoms.

U2 - 10.1186/1471-2490-6-6

DO - 10.1186/1471-2490-6-6

M3 - Article

SN - 1471-2490

VL - 6

JO - BMC Urology

JF - BMC Urology

M1 - 6

ER -

Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

Abstract

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