Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations

G. Mukerji, Y. Yiangou, S. Corcoran, I. S. Selmer, G.D. Smith, C.D. Benham, C. Bountra, S. K. Agarwal, P. Anand

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    131 Citations (Scopus)
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    Abstract

    The recent identification of the cold-menthol sensory receptor (TRPM8; CMR1), provides us with an opportunity to advance our understanding of its role in the pathophysiology of bladder dysfunction, and its potential mediation of the bladder cooling reflex. In this study, we report the distribution of the cool and menthol receptor TRPM8 in the urinary bladder in patients with overactive and painful bladder syndromes, and its relationship with clinical symptoms.
    Original languageEnglish
    Article number6
    JournalBMC Urology
    Volume6
    DOIs
    Publication statusPublished - 2006

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