AimsTo measure in-patient diabetes treatment satisfaction and its relationship to in-patient diabetes care.MethodsIn a cross-sectional study, diabetes in-patient specialist nurses at 58 UK hospitals asked insulin-treated in-patients with diabetes to complete the recently updated Diabetes Treatment Satisfaction Questionnaire for In-patients and a general questionnaire; 1319 in-patients completed these questionnaires.ResultsSatisfaction with the general diabetes treatment items in the Diabetes Treatment Satisfaction Questionnaire for In-patients was high, but there were high levels of extreme dissatisfaction with meal choices, meal quality and lack of similarity of hospital meals to normal domestic choices—23% would never or rarely have made similar meal choices at home. Hyperglycaemia or hypoglycaemia was reported for much of the in-patient stay (20% and 7%, respectively) and 26% reported at least one severe hypoglycaemic episode; these groups had lower satisfaction with the timing of medication in relation to meals (P <0.003). More frequent in-patient hyperglycaemia or hypoglycaemia were associated with significantly poorer overall satisfaction scores and negative well-being scores (both P <0.0001). Previous experience of a multiple daily insulin injection regimen was associated with more dissatisfaction than other regimens (P <0.01). Multiple regression models explained 36% of variability in overall treatment satisfaction, with most (22.4%) accounted for by satisfaction with time spent with a diabetes in-patient specialist nurse (P <0.0001). Self-administration of insulin was independently associated with higher treatment satisfaction (P <0.006) in this model.ConclusionsThe DIPSat programme describes the complex relationships between diabetes in-patient treatment satisfaction and in-patient diabetes care.